ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: glutamate receptor, metabotropic 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000152822 GRM1 9606 + 6:146027646-146437598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000282753 GRM1-001 146029283-146437598 protein_coding
  ENST00000355289 GRM1-019 146029283-146434885 protein_coding
  ENST00000361719 GRM1-201 146027782-146437598 protein_coding
  ENST00000492807 GRM1-002 146027782-146437595 protein_coding
  ENST00000502405 GRM1-018 146027703-146159891 retained_intron
  ENST00000507005 GRM1-017 146027646-146159692 retained_intron
  ENST00000507907 GRM1-020 146029486-146434885 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000282753ENST00000355289ENST00000361719ENST00000492807ENST00000502405ENST00000507005ENST00000507907
Transcript ID HAoEC HUVEC
ENST00000282753 0.032±0.02 0.016±0.02
ENST00000355289 0.017±0.00 0.004±0.00
ENST00000361719 0.013±0.00 N/A
ENST00000492807 0.041±0.02 0.031±0.01
ENST00000502405 0.092±0.06 0.015±0.00
ENST00000507005 N/A 0.023±0.00
ENST00000507907 0.011±0.01 0.024±0.02

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0000187 IEA activation of MAPK activity
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 TAS plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0007186 IDA:IEA G-protein coupled receptor signaling pathway
GO:0007205 IBA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007216 IBA G-protein coupled glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007626 IEA locomotory behavior
GO:0008066 IDA glutamate receptor activity
GO:0008219 IEA cell death
GO:0014069 IBA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030425 IEA dendrite
GO:0038037 IDA G-protein coupled receptor dimeric complex
GO:0038038 IPI G-protein coupled receptor homodimeric complex
GO:0038042 IDA dimeric G-protein coupled receptor signaling pathway
GO:0043005 IEA neuron projection
GO:0043408 IEA regulation of MAPK cascade
GO:0051482 IMP positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051930 IEA regulation of sensory perception of pain
GO:0051966 IBA regulation of synaptic transmission, glutamatergic
GO:0071257 IEA cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026796 grm1a protein_coding Danio_rerio
ENSMUSG00000019828 Grm1 protein_coding Mus_musculus

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