ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: F-box and leucine-rich repeat protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000153558 FBXL2 9606 + 3:33277025-33403662 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000283627 FBXL2-003 33277446-33386476 processed_transcript
  ENST00000421391 FBXL2-008 33277477-33385862 nonsense_mediated_decay
  ENST00000422741 FBXL2-009 33277476-33386633 nonsense_mediated_decay
  ENST00000425973 FBXL2-017 33277472-33373319 nonsense_mediated_decay
  ENST00000432809 FBXL2-004 33277451-33386023 nonsense_mediated_decay
  ENST00000435207 FBXL2-002 33277445-33385621 nonsense_mediated_decay
  ENST00000451636 FBXL2-005 33277453-33385948 nonsense_mediated_decay
  ENST00000460186 FBXL2-019 33372988-33375366 retained_intron
  ENST00000461094 FBXL2-022 33364336-33373618 retained_intron
  ENST00000463698 FBXL2-018 33372341-33373639 retained_intron
  ENST00000463736 FBXL2-007 33277466-33403662 processed_transcript
  ENST00000464164 FBXL2-015 33289669-33373303 processed_transcript
  ENST00000464990 FBXL2-010 33382552-33386625 retained_intron
  ENST00000471208 FBXL2-021 33373276-33373924 retained_intron
  ENST00000483037 FBXL2-013 33278173-33359358 processed_transcript
  ENST00000484457 FBXL2-001 33277422-33388092 protein_coding
  ENST00000492662 FBXL2-020 33373021-33375407 retained_intron
  ENST00000493778 FBXL2-014 33289650-33373311 processed_transcript
  ENST00000497411 FBXL2-016 33277445-33373601 retained_intron
  ENST00000498807 FBXL2-012 33277025-33373295 processed_transcript
  ENST00000507198 FBXL2-006 33277476-33385762 protein_coding
  ENST00000538892 FBXL2-201 33277445-33387265 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000283627ENST00000421391ENST00000422741ENST00000432809ENST00000435207ENST00000451636ENST00000463736ENST00000464990ENST00000484457ENST00000497411ENST00000507198ENST00000538892
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000283627 N/A 2.027±0.49 N/A 2.218±0.00 4.653±2.88
ENST00000421391 N/A N/A N/A N/A 6.914±4.52
ENST00000422741 4.204±0.00 2.538±1.29 N/A 2.916±0.00 2.377±0.94
ENST00000432809 N/A N/A N/A N/A 8.513±4.11
ENST00000435207 N/A N/A N/A N/A 0.935±0.00
ENST00000451636 N/A N/A N/A N/A 0.973±0.27
ENST00000463736 N/A 1.378±0.00 N/A N/A 3.810±2.84
ENST00000464990 N/A 1.059±0.29 N/A N/A 1.735±1.07
ENST00000484457 N/A 0.635±0.29 1.165±0.00 N/A 1.672±1.33
ENST00000497411 N/A N/A N/A N/A 7.697±0.95
ENST00000507198 N/A 1.504±0.57 N/A 3.981±0.00 3.665±1.10
ENST00000538892 2.507±1.47 0.847±0.29 N/A 1.338±0.00 1.705±0.63

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001TS CIL_0001TS_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005737 TAS cytoplasm
GO:0006464 TAS cellular protein modification process
GO:0006508 TAS proteolysis
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006513 IEA protein monoubiquitination
GO:0016020 IDA membrane
GO:0016032 IEA viral process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012135 fbxl2 protein_coding Danio_rerio
ENSMUSG00000032507 Fbxl2 protein_coding Mus_musculus

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