ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ectonucleotide pyrophosphatase/phosphodiesterase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000154269 ENPP3 9606 + 6:131628442-131747418 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357639 ENPP3-201 131637302-131747407 protein_coding
  ENST00000358229 ENPP3-202 131637302-131747407 protein_coding
  ENST00000414305 ENPP3-001 131628461-131747418 protein_coding
  ENST00000423831 ENPP3-003 131637304-131652651 nonsense_mediated_decay
  ENST00000427707 ENPP3-005 131628442-131676797 nonsense_mediated_decay
  ENST00000470930 ENPP3-004 131641455-131674208 processed_transcript
  ENST00000494023 ENPP3-002 131652857-131675378 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000357639ENST00000358229ENST00000414305ENST00000423831ENST00000427707ENST00000470930
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000357639 N/A N/A N/A N/A 0.032±0.02
ENST00000358229 0.028±0.00 0.021±0.01 0.312±0.00 0.045±0.00 0.015±0.01
ENST00000414305 N/A N/A N/A N/A 0.114±0.00
ENST00000423831 N/A 0.154±0.11 N/A N/A 0.039±0.00
ENST00000427707 N/A 0.053±0.02 N/A N/A 0.017±0.01
ENST00000470930 N/A N/A N/A N/A 0.116±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003676 IEA nucleic acid binding
GO:0003824 IEA catalytic activity
GO:0004528 IEA phosphodiesterase I activity
GO:0004551 TAS nucleotide diphosphatase activity
GO:0005044 IEA scavenger receptor activity
GO:0005887 TAS integral component of plasma membrane
GO:0006796 IDA phosphate-containing compound metabolic process
GO:0006898 IEA receptor-mediated endocytosis
GO:0006955 IEA immune response
GO:0008152 IEA metabolic process
GO:0009143 IDA nucleoside triphosphate catabolic process
GO:0016787 IEA hydrolase activity
GO:0030247 IEA polysaccharide binding
GO:0035529 IEA NADH pyrophosphatase activity
GO:0046872 IEA metal ion binding
GO:0047429 IDA nucleoside-triphosphate diphosphatase activity
GO:0048471 IDA perinuclear region of cytoplasm
GO:0070062 IDA extracellular vesicular exosome
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000019989 Enpp3 protein_coding Mus_musculus

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