ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: titin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155657 TTN 9606 - 2:178525989-178830802 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342175 TTN-201 178525989-178807423 protein_coding
  ENST00000342992 TTN-002 178525989-178807421 protein_coding
  ENST00000359218 TTN-202 178525989-178807423 protein_coding
  ENST00000360870 TTN-010 178744405-178807421 protein_coding
  ENST00000412264 TTN-009 178802287-178830802 protein_coding
  ENST00000414766 TTN-005 178636752-178702520 protein_coding
  ENST00000425332 TTN-006 178663627-178667307 protein_coding
  ENST00000426232 TTN-007 178639772-178651520 protein_coding
  ENST00000436599 TTN-004 178786089-178794954 protein_coding
  ENST00000446966 TTN-008 178640077-178651516 protein_coding
  ENST00000448510 TTN-011 178669625-178672418 protein_coding
  ENST00000460472 TTN-003 178525989-178807423 protein_coding
  ENST00000470257 TTN-001 178798495-178807408 retained_intron
  ENST00000589042 TTN-018 178525989-178807423 protein_coding
  ENST00000591111 TTN-019 178525989-178807423 protein_coding
  ENST00000615779 TTN-203 178525989-178807423 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000342992ENST00000360870ENST00000460472
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000342992 0.014±0.00 0.072±0.03 N/A N/A 0.032±0.01
ENST00000360870 0.043±0.00 N/A N/A N/A N/A
ENST00000460472 N/A 0.132±0.08 0.114±0.00 0.122±0.00 0.252±0.32

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000YX CIL_0000YX_0001 CGP
CIL_0000YW CIL_0000YW_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000794 IDA condensed nuclear chromosome
GO:0001701 IEA in utero embryonic development
GO:0002020 IPI protease binding
GO:0002576 TAS platelet degranulation
GO:0003007 IEA heart morphogenesis
GO:0003300 IMP cardiac muscle hypertrophy
GO:0003676 IEA nucleic acid binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005488 IEA binding
GO:0005509 IDA calcium ion binding
GO:0005515 IEA protein binding
GO:0005516 TAS calmodulin binding
GO:0005524 IEA ATP binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005865 IDA striated muscle thin filament
GO:0006468 IEA protein phosphorylation
GO:0006936 NAS muscle contraction
GO:0006941 TAS striated muscle contraction
GO:0007076 IEP mitotic chromosome condensation
GO:0007512 IEA adult heart development
GO:0007596 TAS blood coagulation
GO:0008307 IMP structural constituent of muscle
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0021591 IEA ventricular system development
GO:0030017 IEA sarcomere
GO:0030018 IDA Z disc
GO:0030049 TAS muscle filament sliding
GO:0030168 TAS platelet activation
GO:0030240 IMP skeletal muscle thin filament assembly
GO:0030241 IMP skeletal muscle myosin thick filament assembly
GO:0031430 IDA M band
GO:0031433 ISS telethonin binding
GO:0031672 IEA A band
GO:0031674 IDA I band
GO:0035995 TAS detection of muscle stretch
GO:0042802 IPI identical protein binding
GO:0042805 IPI actinin binding
GO:0043056 IEA forward locomotion
GO:0043621 IDA protein self-association
GO:0045214 IMP sarcomere organization
GO:0045859 IMP regulation of protein kinase activity
GO:0048739 IMP cardiac muscle fiber development
GO:0048769 IMP sarcomerogenesis
GO:0050790 IMP regulation of catalytic activity
GO:0051015 IDA actin filament binding
GO:0051371 IPI muscle alpha-actinin binding
GO:0051592 IDA response to calcium ion
GO:0055002 IEA striated muscle cell development
GO:0055003 IMP cardiac myofibril assembly
GO:0055008 IMP cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction
GO:0060419 IEA heart growth
GO:0070062 IDA extracellular vesicular exosome
GO:0097493 TAS structural molecule activity conferring elasticity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000051747 Ttn protein_coding Mus_musculus

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