ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: adenylate cyclase 8 (brain)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000155897 ADCY8 9606 - 8:130780301-131042426 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286355 ADCY8-001 130780301-131042426 protein_coding
  ENST00000377928 ADCY8-002 130780390-131040333 protein_coding
  ENST00000522949 ADCY8-003 130903772-130990865 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000286355ENST00000377928ENST00000522949
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000286355 0.014±0.00 0.027±0.01 N/A 0.012±0.00
ENST00000377928 N/A 0.033±0.01 0.042±0.00 0.012±0.01
ENST00000522949 N/A 0.069±0.05 N/A 0.077±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004ZP CIL_0004ZP_0001 CGP
CIL_0006ZP CIL_0006ZP_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004016 TAS:IEA adenylate cyclase activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IEA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007611 TAS learning or memory
GO:0007616 IEA long-term memory
GO:0008294 TAS calcium- and calmodulin-responsive adenylate cyclase activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016020 TAS membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031783 adcy8 protein_coding Danio_rerio
ENSMUSG00000022376 Adcy8 protein_coding Mus_musculus

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