ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156113 KCNMA1 9606 - 10:76869601-77638595 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000286627 KCNMA1-001 76884881-77638595 protein_coding
  ENST00000286628 KCNMA1-009 76884877-77637642 protein_coding
  ENST00000354353 KCNMA1-201 76884878-77404025 protein_coding
  ENST00000372403 KCNMA1-004 76877739-77637494 protein_coding
  ENST00000372408 KCNMA1-005 76877597-77637453 protein_coding
  ENST00000372421 KCNMA1-002 76877597-77637562 protein_coding
  ENST00000372437 KCNMA1-006 76877597-77637447 protein_coding
  ENST00000372440 KCNMA1-003 76877597-77637993 protein_coding
  ENST00000372443 KCNMA1-010 76877597-77638369 protein_coding
  ENST00000404771 KCNMA1-008 76877597-77637758 protein_coding
  ENST00000404857 KCNMA1-202 76877869-77404025 protein_coding
  ENST00000406533 KCNMA1-203 76884878-77404025 protein_coding
  ENST00000428546 KCNMA1-019 77012198-77079524 protein_coding
  ENST00000434208 KCNMA1-011 76884116-77110338 protein_coding
  ENST00000450795 KCNMA1-018 76995284-77079550 protein_coding
  ENST00000457953 KCNMA1-007 76877597-77637564 protein_coding
  ENST00000468471 KCNMA1-013 76887465-76887910 processed_transcript
  ENST00000475352 KCNMA1-012 76973993-77019063 processed_transcript
  ENST00000480683 KCNMA1-015 77636199-77637993 protein_coding
  ENST00000481070 KCNMA1-014 77636199-77637789 protein_coding
  ENST00000484343 KCNMA1-017 77071235-77079550 processed_transcript
  ENST00000484507 KCNMA1-016 77063692-77084717 processed_transcript
  ENST00000604624 KCNMA1-020 76869601-77403984 protein_coding
  ENST00000618048 KCNMA1-204 77636205-77637819 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000286627ENST00000286628ENST00000354353ENST00000372403ENST00000372408ENST00000404857ENST00000406533ENST00000428546ENST00000434208ENST00000450795ENST00000480683ENST00000481070ENST00000484507ENST00000604624ENST00000618048
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000286627 N/A 0.180±0.14 N/A N/A 0.146±0.15
ENST00000286628 N/A 0.139±0.16 N/A N/A 0.526±0.47
ENST00000354353 N/A N/A N/A N/A 0.166±0.16
ENST00000372403 N/A 0.278±0.21 N/A 0.499±0.00 N/A
ENST00000372408 N/A N/A N/A N/A 0.030±0.00
ENST00000404857 N/A 0.261±0.25 N/A N/A 0.089±0.13
ENST00000406533 0.262±0.00 0.378±0.27 N/A 0.344±0.00 0.053±0.03
ENST00000428546 2.192±0.00 N/A N/A N/A 0.102±0.08
ENST00000434208 N/A N/A 0.043±0.00 N/A 0.016±0.01
ENST00000450795 N/A 0.100±0.00 N/A N/A 0.091±0.08
ENST00000480683 3.241±1.01 N/A N/A 1.384±0.00 0.337±0.34
ENST00000481070 5.200±0.55 0.578±0.06 0.934±0.00 N/A 0.593±0.85
ENST00000484507 N/A N/A N/A N/A 0.348±0.09
ENST00000604624 N/A N/A N/A N/A 0.005±0.00
ENST00000618048 N/A N/A N/A N/A 0.038±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007JX CIL_0007JX_0001 UCNEbase
CIL_0005E6 CIL_0005E6_0001 CGP
CIL_0008QZ CIL_0008QZ_0001 VISTA
CIL_0008KV CIL_0008KV_0001 VISTA
CIL_0008L3 CIL_0008L3_0001 VISTA
CIL_00087A CIL_00087A_0001 VISTA
CIL_0004CA CIL_0004CA_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0003779 IDA actin binding
GO:0005216 IEA ion channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005901 IDA caveola
GO:0006811 IEA ion transport
GO:0006813 IDA:IEA potassium ion transport
GO:0006970 IDA response to osmotic stress
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0008076 IDA voltage-gated potassium channel complex
GO:0015269 IDA:IEA calcium-activated potassium channel activity
GO:0016020 IEA membrane
GO:0016021 IDA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0030007 IDA cellular potassium ion homeostasis
GO:0034465 IDA response to carbon monoxide
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042391 IDA regulation of membrane potential
GO:0043065 IMP positive regulation of apoptotic process
GO:0045794 IDA negative regulation of cell volume
GO:0046872 IEA metal ion binding
GO:0051592 IDA response to calcium ion
GO:0055085 IEA transmembrane transport
GO:0060072 IMP large conductance calcium-activated potassium channel activity
GO:0060073 IDA micturition
GO:0060083 IDA smooth muscle contraction involved in micturition
GO:0070062 IDA extracellular vesicular exosome
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079840 kcnma1a protein_coding Danio_rerio
ENSMUSG00000063142 Kcnma1 protein_coding Mus_musculus

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