ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: apoptosis-inducing factor, mitochondrion-associated, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156709 AIFM1 9606 - X:130129362-130165887 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287295 AIFM1-001 130129370-130165887 protein_coding
  ENST00000319908 AIFM1-002 130129362-130165879 protein_coding
  ENST00000346424 AIFM1-003 130129362-130165680 protein_coding
  ENST00000416073 AIFM1-005 130129362-130165664 nonsense_mediated_decay
  ENST00000460436 AIFM1-004 130129362-130138040 protein_coding
  ENST00000527892 AIFM1-006 130129362-130165664 nonsense_mediated_decay
  ENST00000529877 AIFM1-007 130147609-130165759 nonsense_mediated_decay
  ENST00000533719 AIFM1-008 130136665-130147928 retained_intron
  ENST00000535724 AIFM1-201 130129365-130165887 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000287295ENST00000346424ENST00000460436ENST00000533719
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000287295 3.833±0.00 17.551±9.25 N/A 10.170±0.00 8.896±4.38
ENST00000346424 20.912±3.96 7.779±2.51 5.983±0.00 N/A 4.366±1.58
ENST00000460436 N/A N/A N/A N/A 0.182±0.00
ENST00000533719 N/A 11.010±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000SZ CIL_0000SZ_0001 CGP
CIL_0000SY CIL_0000SY_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005758 IDA mitochondrial intermembrane space
GO:0005829 ISS cytosol
GO:0006308 TAS DNA catabolic process
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006915 IMP apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0009055 TAS electron carrier activity
GO:0010942 IEA positive regulation of cell death
GO:0016174 TAS NAD(P)H oxidase activity
GO:0016491 IEA oxidoreductase activity
GO:0016651 IDA oxidoreductase activity, acting on NAD(P)H
GO:0030182 IDA neuron differentiation
GO:0030261 TAS chromosome condensation
GO:0032981 IMP mitochondrial respiratory chain complex I assembly
GO:0043065 TAS positive regulation of apoptotic process
GO:0045454 IEA cell redox homeostasis
GO:0046983 IEA protein dimerization activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0051402 IEA neuron apoptotic process
GO:0055114 IEA oxidation-reduction process
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0071949 IEA FAD binding
GO:1902510 IEA regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058088 aifm1 protein_coding Danio_rerio
ENSMUSG00000036932 Aifm1 protein_coding Mus_musculus

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