ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: BUB1 mitotic checkpoint serine/threonine kinase B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000156970 BUB1B 9606 + 15:40161023-40221136 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287598 BUB1B-001 40161026-40221136 protein_coding
  ENST00000412359 BUB1B-003 40161067-40221038 protein_coding
  ENST00000557848 BUB1B-007 40185326-40196734 retained_intron
  ENST00000558151 BUB1B-010 40217417-40220644 retained_intron
  ENST00000558715 BUB1B-011 40161067-40170599 nonsense_mediated_decay
  ENST00000558972 BUB1B-009 40200038-40206274 retained_intron
  ENST00000559414 BUB1B-012 40161043-40176550 processed_transcript
  ENST00000559461 BUB1B-006 40183724-40185481 retained_intron
  ENST00000559733 BUB1B-005 40183714-40202634 nonsense_mediated_decay
  ENST00000559772 BUB1B-008 40185472-40200289 retained_intron
  ENST00000560120 BUB1B-004 40161023-40176621 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000287598ENST00000412359ENST00000558151ENST00000559414
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000287598 N/A 5.660±3.10 2.420±0.00 4.966±3.75
ENST00000412359 N/A 2.621±1.04 5.081±0.00 N/A
ENST00000558151 6.090±0.00 N/A N/A N/A
ENST00000559414 N/A N/A N/A 4.835±0.63

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008W0 CIL_0008W0_0001 VISTA
CIL_00070K CIL_00070K_0001 CGP
CIL_0005IH CIL_0005IH_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000776 IDA kinetochore
GO:0000777 IDA condensed chromosome kinetochore
GO:0000778 IEA condensed nuclear chromosome kinetochore
GO:0000940 IDA condensed chromosome outer kinetochore
GO:0004672 NAS:IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005680 TAS anaphase-promoting complex
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007067 NAS mitotic nuclear division
GO:0007091 IEA metaphase/anaphase transition of mitotic cell cycle
GO:0007093 TAS mitotic cell cycle checkpoint
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0008283 TAS cell proliferation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034501 IPI protein localization to kinetochore
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051233 NAS spindle midzone
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0071459 IEA protein localization to chromosome, centromeric region

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074927 bub1bb protein_coding Danio_rerio
ENSMUSG00000040084 Bub1b protein_coding Mus_musculus

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