ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: tumor necrosis factor receptor superfamily, member 14
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157873 TNFRSF14 9606 + 1:2555639-2565382 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355716 TNFRSF14-001 2556366-2563829 protein_coding
  ENST00000409119 TNFRSF14-009 2556222-2561718 protein_coding
  ENST00000426449 TNFRSF14-011 2555639-2560714 protein_coding
  ENST00000434817 TNFRSF14-008 2555791-2561815 protein_coding
  ENST00000435221 TNFRSF14-007 2555802-2561815 protein_coding
  ENST00000442392 TNFRSF14-013 2556405-2559156 processed_transcript
  ENST00000451778 TNFRSF14-006 2555980-2561815 protein_coding
  ENST00000463471 TNFRSF14-015 2556571-2563749 retained_intron
  ENST00000463835 TNFRSF14-005 2560554-2563504 retained_intron
  ENST00000466750 TNFRSF14-003 2557813-2563826 retained_intron
  ENST00000471768 TNFRSF14-010 2559580-2561542 retained_intron
  ENST00000475523 TNFRSF14-002 2556386-2563829 retained_intron
  ENST00000480305 TNFRSF14-014 2561801-2563452 processed_transcript
  ENST00000482074 TNFRSF14-012 2556406-2558862 retained_intron
  ENST00000482602 TNFRSF14-004 2560682-2565382 processed_transcript
  ENST00000496064 TNFRSF14-016 2556557-2561535 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000355716ENST00000426449ENST00000435221ENST00000451778ENST00000463471ENST00000466750ENST00000475523ENST00000482074ENST00000496064
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000355716 41.518±18.65 6.732±5.03 96.372±0.00 27.766±0.00 13.116±9.13
ENST00000426449 N/A 2.634±0.28 N/A N/A N/A
ENST00000435221 N/A N/A N/A N/A 3.286±0.00
ENST00000451778 N/A N/A N/A N/A 5.692±0.00
ENST00000463471 4.879±0.00 0.874±0.41 N/A N/A 2.758±2.32
ENST00000466750 N/A 0.599±0.15 N/A N/A 2.940±2.85
ENST00000475523 N/A N/A 100.208±0.00 N/A N/A
ENST00000482074 N/A N/A N/A N/A 0.680±0.00
ENST00000496064 N/A N/A N/A N/A 3.113±4.67

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001618 IEA virus receptor activity
GO:0002741 IEA positive regulation of cytokine secretion involved in immune response
GO:0005031 TAS tumor necrosis factor-activated receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006955 TAS immune response
GO:0007166 TAS cell surface receptor signaling pathway
GO:0009615 IEA response to virus
GO:0009897 IEA external side of plasma membrane
GO:0016032 IEA viral process
GO:0031295 TAS T cell costimulation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033209 TAS tumor necrosis factor-mediated signaling pathway
GO:0046642 IEA negative regulation of alpha-beta T cell proliferation
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050829 IEA defense response to Gram-negative bacterium
GO:0050830 IEA defense response to Gram-positive bacterium
GO:2000406 IEA positive regulation of T cell migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068966 TNFRSF14 (1 of 8) protein_coding Danio_rerio
ENSDARG00000068969 TNFRSF14 (2 of 8) protein_coding Danio_rerio
ENSDARG00000068991 TNFRSF14 (3 of 8) protein_coding Danio_rerio
ENSDARG00000068993 TNFRSF14 (4 of 8) protein_coding Danio_rerio
ENSDARG00000089901 TNFRSF14 (5 of 8) protein_coding Danio_rerio
ENSDARG00000092381 TNFRSF14 (6 of 8) protein_coding Danio_rerio
ENSDARG00000092892 TNFRSF14 (7 of 8) protein_coding Danio_rerio
ENSDARG00000095193 TNFRSF14 (8 of 8) protein_coding Danio_rerio
ENSMUSG00000042333 Tnfrsf14 protein_coding Mus_musculus

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