ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: neuregulin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158458 NRG2 9606 - 5:139846779-140043299 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000289409 NRG2-002 139847917-140043069 protein_coding
  ENST00000289422 NRG2-012 139847649-140043147 protein_coding
  ENST00000340391 NRG2-006 139847917-139904397 protein_coding
  ENST00000358522 NRG2-007 139847917-140043069 protein_coding
  ENST00000361474 NRG2-001 139847675-140043294 protein_coding
  ENST00000378238 NRG2-011 139851753-140043069 nonsense_mediated_decay
  ENST00000518130 NRG2-010 139869538-139904310 processed_transcript
  ENST00000519478 NRG2-009 139869399-139871803 processed_transcript
  ENST00000541337 NRG2-201 139846779-140043299 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000289409ENST00000289422ENST00000340391ENST00000361474ENST00000378238ENST00000518130ENST00000519478ENST00000541337
Transcript ID BECs HAoEC HUVEC
ENST00000289409 N/A N/A 0.082±0.09
ENST00000289422 N/A N/A 0.032±0.00
ENST00000340391 0.205±0.00 0.420±0.20 0.113±0.08
ENST00000361474 0.072±0.00 0.095±0.04 0.079±0.07
ENST00000378238 N/A 0.405±0.29 0.051±0.02
ENST00000518130 0.199±0.00 0.719±0.21 0.132±0.05
ENST00000519478 N/A N/A 0.101±0.00
ENST00000541337 N/A 0.147±0.08 0.052±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000540 CIL_000540_0001 CGP
CIL_00062Q CIL_00062Q_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS:IEA receptor binding
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008083 IEA growth factor activity
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009790 IEA embryo development
GO:0016021 IEA integral component of membrane
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077818 nrg2a protein_coding Danio_rerio
ENSDARG00000086585 nrg2b protein_coding Danio_rerio
ENSMUSG00000060275 Nrg2 protein_coding Mus_musculus

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