ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ADAM metallopeptidase with thrombospondin type 1 motif, 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158859 ADAMTS4 9606 - 1:161184308-161199056 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367995 ADAMTS4-002 161195979-161199053 protein_coding
  ENST00000367996 ADAMTS4-001 161184308-161199056 protein_coding
  ENST00000478394 ADAMTS4-003 161194162-161195751 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000367995ENST00000367996
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000367995 N/A 3.482±2.44 N/A 7.262±0.00 2.947±1.96
ENST00000367996 2.411±0.41 2.222±1.41 2.316±0.00 4.891±0.00 1.912±1.42

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 TAS skeletal system development
GO:0002020 IPI protease binding
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0006508 IEA proteolysis
GO:0008233 TAS peptidase activity
GO:0008237 TAS metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0031012 IDA:IEA extracellular matrix
GO:0042742 IEA defense response to bacterium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000006403 Adamts4 protein_coding Mus_musculus

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