ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: actin, alpha, cardiac muscle 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159251 ACTC1 9606 - 15:34788096-34796139 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290378 ACTC1-001 34788096-34796139 protein_coding
  ENST00000557860 ACTC1-003 34791158-34792851 processed_transcript
  ENST00000560563 ACTC1-004 34791701-34792522 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000290378ENST00000557860
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000290378 0.037±0.01 N/A 0.056±0.04
ENST00000557860 0.180±0.06 0.315±0.00 0.407±0.23

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008VH CIL_0008VH_0001 VISTA
CIL_0005II CIL_0005II_0002 CGP
CIL_0006HF CIL_0006HF_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005524 IDA ATP binding
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005884 IDA actin filament
GO:0005925 IDA focal adhesion
GO:0006200 IDA ATP catabolic process
GO:0006915 ISS apoptotic process
GO:0016020 IDA membrane
GO:0016887 IDA ATPase activity
GO:0017022 IPI myosin binding
GO:0030017 IDA sarcomere
GO:0030048 IDA actin filament-based movement
GO:0030049 TAS muscle filament sliding
GO:0030240 ISS skeletal muscle thin filament assembly
GO:0031032 ISS actomyosin structure organization
GO:0031674 ISS I band
GO:0033275 IMP actin-myosin filament sliding
GO:0042493 IEA response to drug
GO:0042643 IDA actomyosin, actin portion
GO:0043066 IEA negative regulation of apoptotic process
GO:0045471 IEA response to ethanol
GO:0055003 ISS cardiac myofibril assembly
GO:0055008 ISS cardiac muscle tissue morphogenesis
GO:0060047 IMP heart contraction
GO:0060048 IEA cardiac muscle contraction
GO:0070062 IDA extracellular vesicular exosome
GO:0070252 IEA actin-mediated cell contraction
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036371 acta1a protein_coding Danio_rerio
ENSDARG00000042535 actc1a protein_coding Danio_rerio
ENSDARG00000055618 acta1b protein_coding Danio_rerio
ENSDARG00000057911 zgc:86709 protein_coding Danio_rerio
ENSDARG00000076126 si:ch73-187m15.4 protein_coding Danio_rerio
ENSMUSG00000068614 Actc1 protein_coding Mus_musculus

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