ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: single-minded family bHLH transcription factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159263 SIM2 9606 + 21:36699133-36749917 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290399 SIM2-001 36699134-36749917 protein_coding
  ENST00000431229 SIM2-004 36709181-36745871 protein_coding
  ENST00000460783 SIM2-003 36699133-36710613 processed_transcript
  ENST00000481185 SIM2-002 36699134-36746324 retained_intron
  ENST00000483178 SIM2-005 36712566-36720587 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000290399ENST00000431229ENST00000460783ENST00000481185ENST00000483178
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000290399 0.028±0.00 0.073±0.03 0.192±0.00 0.255±0.00 0.046±0.03
ENST00000431229 N/A 0.045±0.00 N/A N/A N/A
ENST00000460783 0.033±0.00 0.107±0.05 0.157±0.00 N/A 0.013±0.00
ENST00000481185 N/A 0.035±0.00 N/A N/A 0.028±0.02
ENST00000483178 N/A 0.185±0.00 N/A N/A 0.105±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006Z7 CIL_0006Z7_0001 CGP
CIL_0006Z8 CIL_0006Z8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007399 IEA nervous system development
GO:0009880 IEA embryonic pattern specification
GO:0030154 IEA cell differentiation
GO:0030324 IEA lung development
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046982 IEA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000062713 Sim2 protein_coding Mus_musculus

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