ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: DNA fragmentation factor, 45kDa, alpha polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160049 DFFA 9606 - 1:10456522-10472526 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000377036 DFFA-002 10462468-10472488 protein_coding
  ENST00000377038 DFFA-001 10456522-10472526 protein_coding
  ENST00000476658 DFFA-003 10461643-10472479 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000377036ENST00000377038
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000377036 13.105±1.53 21.999±10.10 N/A 11.464±0.00 8.365±3.29
ENST00000377038 5.627±0.56 8.687±3.44 1.370±0.00 3.345±0.00 6.210±3.42

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008IM CIL_0008IM_0001 VISTA
CIL_0007WE CIL_0007WE_0001 VISTA
CIL_00085P CIL_00085P_0001 VISTA
CIL_00082Y CIL_00082Y_0001 VISTA
CIL_0008S2 CIL_0008S2_0001 VISTA
CIL_00019O CIL_00019O_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006309 TAS apoptotic DNA fragmentation
GO:0006915 TAS:IEA apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0007165 IEA signal transduction
GO:0043065 IEA positive regulation of apoptotic process
GO:0070242 IEA thymocyte apoptotic process
GO:1900118 IDA negative regulation of execution phase of apoptosis
GO:1902511 IDA negative regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055770 dffa protein_coding Danio_rerio
ENSMUSG00000028974 Dffa protein_coding Mus_musculus

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