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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: cystathionine-beta-synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160200 CBS 9606 - 21:43053191-43076943 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352178 CBS-001 43053191-43076378 protein_coding
  ENST00000359624 CBS-002 43053191-43076362 protein_coding
  ENST00000398158 CBS-004 43053191-43075831 protein_coding
  ENST00000398165 CBS-003 43053191-43075945 protein_coding
  ENST00000430013 CBS-014 43055598-43060546 protein_coding
  ENST00000441030 CBS-007 43065616-43076943 protein_coding
  ENST00000451248 CBS-016 43053755-43058941 protein_coding
  ENST00000458223 CBS-015 43055583-43058954 protein_coding
  ENST00000461686 CBS-005 43053191-43068404 retained_intron
  ENST00000462349 CBS-013 43053789-43059739 retained_intron
  ENST00000465732 CBS-009 43068321-43075864 processed_transcript
  ENST00000470912 CBS-008 43066243-43075945 processed_transcript
  ENST00000478709 CBS-017 43075107-43076288 processed_transcript
  ENST00000486098 CBS-012 43061919-43063248 retained_intron
  ENST00000488526 CBS-010 43068404-43073508 processed_transcript
  ENST00000491776 CBS-006 43055072-43060520 retained_intron
  ENST00000496485 CBS-011 43059276-43064227 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000352178ENST00000359624ENST00000398165ENST00000441030ENST00000461686ENST00000462349ENST00000465732ENST00000470912ENST00000478709ENST00000486098ENST00000488526ENST00000491776
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000352178 0.085±0.00 0.145±0.00 N/A N/A 0.243±0.11
ENST00000359624 N/A 0.220±0.12 N/A N/A 0.135±0.07
ENST00000398165 N/A 0.153±0.04 N/A N/A 0.165±0.07
ENST00000441030 N/A N/A N/A N/A 0.262±0.00
ENST00000461686 0.076±0.00 0.200±0.07 0.139±0.00 N/A 0.293±0.13
ENST00000462349 0.216±0.00 0.298±0.06 0.772±0.00 N/A 1.128±1.51
ENST00000465732 N/A N/A N/A N/A 0.987±0.10
ENST00000470912 N/A N/A N/A N/A 0.564±0.04
ENST00000478709 N/A 0.700±0.13 N/A 0.583±0.00 1.058±1.27
ENST00000486098 N/A 0.241±0.00 N/A N/A 0.575±0.16
ENST00000488526 N/A N/A N/A N/A 0.630±0.13
ENST00000491776 0.270±0.00 0.307±0.14 N/A 0.100±0.00 0.617±0.88

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000D3 CIL_0000D3_0001 CGP
CIL_0000MQ CIL_0000MQ_0002 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000096 TAS sulfur amino acid metabolic process
GO:0004122 IDA:IEA cystathionine beta-synthase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006535 IEA cysteine biosynthetic process from serine
GO:0006563 IDA L-serine metabolic process
GO:0006565 IDA L-serine catabolic process
GO:0019343 IEA cysteine biosynthetic process via cystathionine
GO:0019346 TAS transsulfuration
GO:0019448 IDA L-cysteine catabolic process
GO:0019899 IPI enzyme binding
GO:0020037 IMP heme binding
GO:0030170 IDA pyridoxal phosphate binding
GO:0030554 IEA adenyl nucleotide binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043418 IDA homocysteine catabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050667 IDA homocysteine metabolic process
GO:0070814 ISS hydrogen sulfide biosynthetic process
GO:0072341 IDA modified amino acid binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010946 cbsb protein_coding Danio_rerio
ENSDARG00000053500 cbsa protein_coding Danio_rerio
ENSMUSG00000024039 Cbs protein_coding Mus_musculus

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