ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: inducible T-cell co-stimulator ligand
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160223 ICOSLG 9606 - 21:44222991-44240966 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344330 ICOSLG-003 44222991-44240840 protein_coding
  ENST00000400377 ICOSLG-002 44226834-44240966 protein_coding
  ENST00000400379 ICOSLG-004 44226834-44240945 protein_coding
  ENST00000407780 ICOSLG-001 44222991-44240945 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000400379ENST00000407780
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000400379 N/A 0.040±0.02 N/A N/A 0.070±0.01
ENST00000407780 1.386±0.00 0.208±0.10 0.191±0.00 0.618±0.00 0.541±0.47

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005102 TAS receptor binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006952 NAS defense response
GO:0006972 NAS hyperosmotic response
GO:0007165 NAS signal transduction
GO:0016021 NAS integral component of membrane
GO:0031295 TAS T cell costimulation
GO:0042104 TAS positive regulation of activated T cell proliferation
GO:0042110 NAS T cell activation
GO:0042113 IEA B cell activation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000000732 Icosl protein_coding Mus_musculus

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