ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: spectrin, beta, non-erythrocytic 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160460 SPTBN4 9606 + 19:40466241-40576464 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338932 SPTBN4-201 40467219-40576458 protein_coding
  ENST00000352632 SPTBN4-001 40466241-40576464 protein_coding
  ENST00000392023 SPTBN4-004 40530488-40560752 protein_coding
  ENST00000392025 SPTBN4-202 40466241-40576459 protein_coding
  ENST00000593816 SPTBN4-009 40571046-40575605 processed_transcript
  ENST00000593932 SPTBN4-006 40530766-40534856 retained_intron
  ENST00000595535 SPTBN4-003 40466241-40560507 protein_coding
  ENST00000595690 SPTBN4-008 40571640-40575577 retained_intron
  ENST00000596411 SPTBN4-007 40571544-40576458 retained_intron
  ENST00000596900 SPTBN4-005 40530526-40555302 retained_intron
  ENST00000597389 SPTBN4-012 40512614-40575569 nonsense_mediated_decay
  ENST00000598249 SPTBN4-011 40467219-40575842 protein_coding
  ENST00000598775 SPTBN4-014 40497429-40502492 retained_intron
  ENST00000599926 SPTBN4-013 40571039-40575663 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000338932ENST00000352632ENST00000392023ENST00000392025ENST00000593816ENST00000593932ENST00000595535ENST00000595690ENST00000596411ENST00000596900ENST00000597389ENST00000598249ENST00000598775ENST00000599926
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000338932 N/A 0.112±0.00 N/A N/A 0.008±0.00
ENST00000352632 N/A 0.206±0.12 N/A N/A 0.010±0.00
ENST00000392023 0.015±0.00 0.523±0.37 N/A N/A 0.047±0.04
ENST00000392025 N/A 0.165±0.02 N/A N/A 0.010±0.00
ENST00000593816 N/A N/A N/A N/A 0.141±0.00
ENST00000593932 N/A N/A 0.056±0.00 N/A 0.020±0.00
ENST00000595535 N/A 0.152±0.08 N/A N/A 0.010±0.01
ENST00000595690 N/A 0.054±0.00 N/A N/A 0.074±0.00
ENST00000596411 0.071±0.00 0.006±0.00 N/A N/A 0.049±0.05
ENST00000596900 0.020±0.00 N/A N/A N/A 0.019±0.00
ENST00000597389 N/A N/A N/A N/A 0.010±0.01
ENST00000598249 N/A N/A N/A N/A 0.007±0.00
ENST00000598775 N/A N/A N/A 0.336±0.00 0.168±0.00
ENST00000599926 0.111±0.00 N/A N/A N/A 0.199±0.16

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002028 ISS regulation of sodium ion transport
GO:0003779 IEA actin binding
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IEA protein binding
GO:0005543 IEA phospholipid binding
GO:0005737 ISS cytoplasm
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0005912 ISS adherens junction
GO:0007016 TAS cytoskeletal anchoring at plasma membrane
GO:0007409 ISS axonogenesis
GO:0007411 TAS axon guidance
GO:0007605 ISS sensory perception of sound
GO:0007628 ISS adult walking behavior
GO:0008091 IEA spectrin
GO:0009566 IEA fertilization
GO:0010459 ISS negative regulation of heart rate
GO:0016020 IDA membrane
GO:0016192 TAS vesicle-mediated transport
GO:0016363 ISS nuclear matrix
GO:0016605 ISS PML body
GO:0019226 ISS transmission of nerve impulse
GO:0019902 IPI phosphatase binding
GO:0021952 ISS central nervous system projection neuron axonogenesis
GO:0022414 IEA reproductive process
GO:0030424 IEA axon
GO:0030506 ISS ankyrin binding
GO:0030507 ISS spectrin binding
GO:0030534 IEA adult behavior
GO:0033135 ISS regulation of peptidyl-serine phosphorylation
GO:0033268 ISS node of Ranvier
GO:0033270 IEA paranode region of axon
GO:0034613 IEA cellular protein localization
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0043025 ISS neuronal cell body
GO:0043194 ISS axon initial segment
GO:0043203 ISS axon hillock
GO:0045162 ISS clustering of voltage-gated sodium channels
GO:0051693 IEA actin filament capping
GO:0061337 ISS cardiac conduction
GO:0070062 IDA extracellular vesicular exosome
GO:0070852 ISS cell body fiber
GO:0090002 ISS establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000092624 SPTBN4 protein_coding Danio_rerio
ENSMUSG00000011751 Sptbn4 protein_coding Mus_musculus

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