ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: BR serine/threonine kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160469 BRSK1 9606 + 19:55282072-55312533 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309383 BRSK1-001 55284166-55312533 protein_coding
  ENST00000326848 BRSK1-003 55302234-55312533 protein_coding
  ENST00000585418 BRSK1-002 55284421-55302921 protein_coding
  ENST00000586626 BRSK1-007 55303146-55304667 retained_intron
  ENST00000588584 BRSK1-008 55304048-55305527 processed_transcript
  ENST00000590333 BRSK1-004 55282072-55312533 protein_coding
  ENST00000591774 BRSK1-006 55302066-55304073 protein_coding
  ENST00000592539 BRSK1-005 55282204-55294248 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000309383ENST00000326848ENST00000585418ENST00000586626ENST00000588584ENST00000590333ENST00000591774ENST00000592539
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000309383 0.042±0.00 N/A N/A N/A
ENST00000326848 0.052±0.00 0.097±0.07 0.295±0.00 0.070±0.06
ENST00000585418 N/A 0.088±0.07 0.315±0.00 0.065±0.02
ENST00000586626 0.620±0.00 N/A N/A 0.210±0.05
ENST00000588584 N/A N/A N/A 0.087±0.05
ENST00000590333 0.101±0.00 0.181±0.12 N/A 0.035±0.03
ENST00000591774 N/A 0.554±0.31 0.253±0.00 0.199±0.16
ENST00000592539 N/A 0.634±0.00 N/A 0.195±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000A2 CIL_0000A2_0001 CGP
CIL_00009Z CIL_00009Z_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IC:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 ISS centrosome
GO:0005886 IDA plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007269 ISS neurotransmitter secretion
GO:0007409 ISS axonogenesis
GO:0008021 ISS synaptic vesicle
GO:0009411 IDA response to UV
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019901 IEA protein kinase binding
GO:0030010 ISS establishment of cell polarity
GO:0030054 IDA cell junction
GO:0030182 ISS neuron differentiation
GO:0031572 IDA G2 DNA damage checkpoint
GO:0043015 ISS gamma-tubulin binding
GO:0048812 IEA neuron projection morphogenesis
GO:0050321 ISS tau-protein kinase activity
GO:0051298 ISS centrosome duplication

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077124 BRSK1 (1 of 2) protein_coding Danio_rerio
ENSDARG00000077545 BRSK1 (2 of 2) protein_coding Danio_rerio
ENSMUSG00000035390 Brsk1 protein_coding Mus_musculus

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