ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: guanylate binding protein 2, interferon-inducible
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162645 GBP2 9606 - 1:89106132-89150456 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370466 GBP2-002 89108000-89126114 protein_coding
  ENST00000463660 GBP2-003 89110187-89120220 processed_transcript
  ENST00000464839 GBP2-001 89106132-89150456 nonsense_mediated_decay
  ENST00000493802 GBP2-004 89108117-89113050 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000370466ENST00000463660ENST00000464839ENST00000493802
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000370466 8.575±4.93 8.988±2.08 3.906±0.00 44.436±0.00 12.877±9.30
ENST00000463660 N/A N/A N/A N/A 0.608±0.06
ENST00000464839 1.946±0.00 N/A 1.833±0.00 N/A 0.805±0.41
ENST00000493802 39.034±2.47 2.965±0.01 15.882±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000033 CIL_000033_0004 CGP
CIL_000033 CIL_000033_0006 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0006184 IEA GTP catabolic process
GO:0006955 TAS immune response
GO:0016020 IEA membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0020005 IEA symbiont-containing vacuole membrane
GO:0031410 IEA cytoplasmic vesicle
GO:0035458 IEA cellular response to interferon-beta
GO:0042832 IEA defense response to protozoan
GO:0044406 IEA adhesion of symbiont to host
GO:0050830 IEA defense response to Gram-positive bacterium
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071346 IEA cellular response to interferon-gamma

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005627 CABZ01068209.1 protein_coding Danio_rerio
ENSDARG00000034063 CABZ01068208.1 protein_coding Danio_rerio
ENSDARG00000038668 gbp1 protein_coding Danio_rerio
ENSDARG00000038669 gbp2 protein_coding Danio_rerio
ENSDARG00000068857 gbp4 protein_coding Danio_rerio
ENSMUSG00000028270 Gbp2 protein_coding Mus_musculus

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