ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: MAD2 mitotic arrest deficient-like 1 (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164109 MAD2L1 9606 - 4:120055608-120067074 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296509 MAD2L1-001 120055608-120067074 protein_coding
  ENST00000333047 MAD2L1-004 120059437-120066833 nonsense_mediated_decay
  ENST00000504707 MAD2L1-003 120059828-120066858 nonsense_mediated_decay
  ENST00000511295 MAD2L1-002 120065451-120066821 retained_intron
  ENST00000512484 MAD2L1-005 120059828-120061036 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000296509ENST00000333047ENST00000504707ENST00000511295ENST00000512484
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000296509 0.439±0.19 1.588±1.07 N/A 1.575±0.00 1.345±0.83
ENST00000333047 4.799±3.57 7.400±3.90 0.391±0.00 10.156±0.00 5.328±3.21
ENST00000504707 N/A 2.031±0.04 N/A N/A N/A
ENST00000511295 N/A N/A N/A N/A 22.216±20.24
ENST00000512484 1.775±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006YP CIL_0006YP_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 IEA mitotic sister chromatid segregation
GO:0000278 TAS mitotic cell cycle
GO:0000775 IEA chromosome, centromeric region
GO:0000776 IDA kinetochore
GO:0000922 IEA spindle pole
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005643 IDA nuclear pore
GO:0005829 IDA cytosol
GO:0007093 IGI mitotic cell cycle checkpoint
GO:0007094 TAS mitotic spindle assembly checkpoint
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0042177 IDA negative regulation of protein catabolic process
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043066 IMP negative regulation of apoptotic process
GO:0045930 IMP negative regulation of mitotic cell cycle
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0060564 IDA negative regulation of mitotic anaphase-promoting complex activity
GO:0072686 IDA mitotic spindle
GO:0090267 IMP positive regulation of mitotic cell cycle spindle assembly checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004713 mad2l1 protein_coding Danio_rerio
ENSMUSG00000029910 Mad2l1 protein_coding Mus_musculus

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