ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: peptidase (mitochondrial processing) alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165688 PMPCA 9606 + 9:136410570-136423761 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371717 PMPCA-001 136410570-136423761 protein_coding
  ENST00000371720 PMPCA-004 136410658-136416555 retained_intron
  ENST00000399219 PMPCA-007 136410661-136423760 protein_coding
  ENST00000444897 PMPCA-003 136417194-136423760 protein_coding
  ENST00000462616 PMPCA-002 136416067-136420933 retained_intron
  ENST00000610649 PMPCA-008 136411118-136416297 processed_transcript
  ENST00000612553 PMPCA-005 136410641-136416904 retained_intron
  ENST00000614402 PMPCA-010 136410674-136412965 retained_intron
  ENST00000619192 PMPCA-011 136410644-136412606 retained_intron
  ENST00000620412 PMPCA-009 136410658-136412504 retained_intron
  ENST00000620895 PMPCA-012 136412172-136417195 retained_intron
  ENST00000622209 PMPCA-006 136410660-136416845 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000371717ENST00000399219ENST00000444897ENST00000462616ENST00000612553ENST00000619192
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000371717 20.458±0.00 35.663±14.03 N/A N/A 23.193±15.03
ENST00000399219 44.371±0.00 26.072±5.64 18.177±0.00 31.493±0.00 9.519±6.38
ENST00000444897 N/A N/A 6.996±0.00 N/A N/A
ENST00000462616 N/A N/A N/A N/A 3.563±4.41
ENST00000612553 N/A N/A N/A N/A 1.214±0.00
ENST00000619192 N/A N/A N/A N/A 114.460±11.90

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002E3 CIL_0002E3_0002 CGP
CIL_00034J CIL_00034J_0001 CGP
CIL_00070Y CIL_00070Y_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004222 TAS metalloendopeptidase activity
GO:0005615 IDA extracellular space
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0006508 TAS proteolysis
GO:0006626 TAS protein targeting to mitochondrion
GO:0008152 IEA metabolic process
GO:0044267 TAS cellular protein metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000026926 Pmpca protein_coding Mus_musculus

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