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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: junctional adhesion molecule 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166086 JAM3 9606 + 11:134068925-134152001 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299106 JAM3-001 134068925-134152001 protein_coding
  ENST00000441717 JAM3-002 134069071-134151751 protein_coding
  ENST00000524969 JAM3-006 134126339-134144996 processed_transcript
  ENST00000531302 JAM3-008 134069085-134145431 retained_intron
  ENST00000532165 JAM3-007 134139640-134145012 processed_transcript
  ENST00000532252 JAM3-004 134069071-134144826 nonsense_mediated_decay
  ENST00000533711 JAM3-010 134147798-134149208 retained_intron
  ENST00000534549 JAM3-005 134069071-134144934 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000299106ENST00000441717ENST00000532252
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000299106 3.368±0.00 18.836±4.37 3.876±0.00 26.125±14.31
ENST00000441717 7.638±0.00 16.966±2.24 5.908±0.00 44.613±40.30
ENST00000532252 N/A N/A N/A 142.936±14.66

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004R4 CIL_0004R4_0003 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IDA angiogenesis
GO:0001780 IEA neutrophil homeostasis
GO:0002250 IEA adaptive immune response
GO:0002318 IEA myeloid progenitor cell differentiation
GO:0002523 IEA leukocyte migration involved in inflammatory response
GO:0005178 IPI integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005923 IEA tight junction
GO:0007160 IEA cell-matrix adhesion
GO:0007283 IEA spermatogenesis
GO:0007286 IEA spermatid development
GO:0007596 TAS blood coagulation
GO:0016021 IEA integral component of membrane
GO:0016477 IEA cell migration
GO:0019226 IEA transmission of nerve impulse
GO:0030010 IEA establishment of cell polarity
GO:0030057 IDA desmosome
GO:0030198 TAS extracellular matrix organization
GO:0031103 IEA axon regeneration
GO:0033010 IEA paranodal junction
GO:0042552 IEA myelination
GO:0042803 IEA protein homodimerization activity
GO:0043220 IEA Schmidt-Lanterman incisure
GO:0044291 IDA cell-cell contact zone
GO:0046982 IEA protein heterodimerization activity
GO:0050900 TAS leukocyte migration
GO:0090022 IDA regulation of neutrophil chemotaxis
GO:0090138 IEA regulation of actin cytoskeleton organization by cell-cell adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061794 jam3b protein_coding Danio_rerio
ENSDARG00000086037 jam3a protein_coding Danio_rerio
ENSMUSG00000031990 Jam3 protein_coding Mus_musculus

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