ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: fibrillin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166147 FBN1 9606 - 15:48408306-48645849 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316623 FBN1-001 48408306-48645849 protein_coding
  ENST00000537463 FBN1-003 48430764-48645709 nonsense_mediated_decay
  ENST00000558230 FBN1-006 48642847-48644832 processed_transcript
  ENST00000559133 FBN1-004 48410074-48467991 nonsense_mediated_decay
  ENST00000560355 FBN1-002 48640989-48645721 protein_coding
  ENST00000560720 FBN1-008 48427944-48432891 retained_intron
  ENST00000560820 FBN1-007 48437622-48445412 retained_intron
  ENST00000561429 FBN1-009 48411201-48416716 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000316623ENST00000537463ENST00000559133ENST00000560355
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000316623 0.822±0.00 4.344±1.43 N/A 8.574±0.00 8.332±9.71
ENST00000537463 N/A 2.615±0.00 N/A N/A 31.757±14.14
ENST00000559133 2.165±0.51 15.312±4.38 1.005±0.00 16.862±0.00 13.512±5.57
ENST00000560355 N/A N/A 0.601±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008GC CIL_0008GC_0001 VISTA
CIL_0004NG CIL_0004NG_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001527 IDA microfibril
GO:0001656 IEA metanephros development
GO:0001822 IEA kidney development
GO:0005201 IDA:IEA extracellular matrix structural constituent
GO:0005509 IEA:IDA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005578 IEA:IDA proteinaceous extracellular matrix
GO:0005604 IDA basement membrane
GO:0005615 IDA extracellular space
GO:0007507 IMP heart development
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0031012 IDA extracellular matrix
GO:0035582 ISS sequestering of BMP in extracellular matrix
GO:0035583 ISS sequestering of TGFbeta in extracellular matrix
GO:0070062 IDA extracellular vesicular exosome
GO:0071560 IEA cellular response to transforming growth factor beta stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027204 Fbn1 protein_coding Mus_musculus

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