ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166396 SERPINB7 9606 + 18:63752935-63805376 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336429 SERPINB7-201 63753047-63805376 protein_coding
  ENST00000398019 SERPINB7-001 63775410-63805370 protein_coding
  ENST00000425392 SERPINB7-002 63752935-63796312 protein_coding
  ENST00000431370 SERPINB7-005 63777977-63796313 protein_coding
  ENST00000447428 SERPINB7-004 63777777-63798643 protein_coding
  ENST00000540675 SERPINB7-202 63775375-63805376 protein_coding
  ENST00000546027 SERPINB7-203 63777777-63805376 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHMVEC-DHUVECENST00000336429ENST00000398019ENST00000447428ENST00000540675ENST00000546027
Transcript ID BECs HMVEC-D HUVEC
ENST00000336429 N/A 0.008±0.00 0.003±0.00
ENST00000398019 0.056±0.00 N/A N/A
ENST00000447428 N/A N/A 0.077±0.00
ENST00000540675 0.017±0.00 N/A N/A
ENST00000546027 N/A 0.069±0.00 0.041±0.03

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000160 CIL_000160_000A CGP
CIL_000160 CIL_000160_0005 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0032914 IEA positive regulation of transforming growth factor beta1 production
GO:0032967 IEA positive regulation of collagen biosynthetic process
GO:0072126 IEA positive regulation of glomerular mesangial cell proliferation
GO:0090362 IEA positive regulation of platelet-derived growth factor production

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 serpinb14 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 protein_coding Danio_rerio
ENSMUSG00000067001 Serpinb7 protein_coding Mus_musculus

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