ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166401 SERPINB8 9606 + 18:63969925-64005667 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295211 SERPINB8-003 63979808-63987396 protein_coding
  ENST00000353706 SERPINB8-201 63970029-63989371 protein_coding
  ENST00000397985 SERPINB8-001 63969925-63989374 protein_coding
  ENST00000397988 SERPINB8-002 63970119-63986653 protein_coding
  ENST00000441827 SERPINB8-006 63970505-63983647 protein_coding
  ENST00000448851 SERPINB8-005 63970249-63981786 protein_coding
  ENST00000493661 SERPINB8-004 63985176-64005667 protein_coding
  ENST00000542677 SERPINB8-202 63970029-63989371 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000295211ENST00000353706ENST00000397985ENST00000397988ENST00000542677
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000295211 10.423±1.73 10.121±7.03 N/A 8.678±0.00 5.657±2.37
ENST00000353706 1.747±0.38 1.898±1.04 0.954±0.00 7.061±0.00 3.205±1.84
ENST00000397985 0.980±0.00 2.058±1.12 N/A 3.723±0.00 2.776±1.26
ENST00000397988 N/A N/A N/A N/A 2.123±0.62
ENST00000542677 0.780±0.01 1.198±0.55 3.836±0.00 2.613±0.00 2.152±0.97

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00076K CIL_00076K_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005829 IDA cytosol
GO:0010951 IDA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 serpinb14 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 protein_coding Danio_rerio
ENSMUSG00000026315 Serpinb8 protein_coding Mus_musculus

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