ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: caseinolytic mitochondrial matrix peptidase chaperone subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166855 CLPX 9606 - 15:65148219-65185342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300107 CLPX-001 65148219-65185342 protein_coding
  ENST00000558103 CLPX-006 65158191-65162647 retained_intron
  ENST00000558958 CLPX-002 65156686-65185342 retained_intron
  ENST00000559152 CLPX-003 65150514-65185216 nonsense_mediated_decay
  ENST00000559218 CLPX-005 65166651-65184484 protein_coding
  ENST00000560166 CLPX-007 65154679-65155851 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000300107ENST00000558958ENST00000559152ENST00000560166
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000300107 1.462±0.00 2.175±1.17 0.710±0.00 3.957±0.00 3.911±2.04
ENST00000558958 N/A 3.160±1.39 N/A 3.292±0.00 3.018±1.69
ENST00000559152 1.666±0.00 3.955±1.14 3.429±0.00 5.702±0.00 4.068±2.56
ENST00000560166 N/A 2.906±0.00 N/A N/A 4.211±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007RY CIL_0007RY_0001 VISTA
CIL_0006TY CIL_0006TY_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004176 IDA ATP-dependent peptidase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0005759 IDA mitochondrial matrix
GO:0006200 IDA ATP catabolic process
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006457 IEA protein folding
GO:0008134 IEA transcription factor binding
GO:0009368 IDA endopeptidase Clp complex
GO:0009841 IDA mitochondrial endopeptidase Clp complex
GO:0010952 IDA positive regulation of peptidase activity
GO:0016504 IDA peptidase activator activity
GO:0016887 ISS:IEA ATPase activity
GO:0042645 IDA mitochondrial nucleoid
GO:0046872 IEA metal ion binding
GO:0051082 IEA unfolded protein binding
GO:0051603 IDA proteolysis involved in cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029063 clpxa protein_coding Danio_rerio
ENSDARG00000067796 clpxb protein_coding Danio_rerio
ENSDARG00000086455 CLPX (3 of 3) protein_coding Danio_rerio
ENSMUSG00000015357 Clpx protein_coding Mus_musculus

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