ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein disulfide isomerase family A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167004 PDIA3 9606 + 15:43746392-43773279 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300289 PDIA3-001 43746392-43773279 protein_coding
  ENST00000434494 PDIA3-004 43746453-43771545 nonsense_mediated_decay
  ENST00000446523 PDIA3-002 43746453-43756766 nonsense_mediated_decay
  ENST00000455250 PDIA3-006 43746612-43768495 nonsense_mediated_decay
  ENST00000469684 PDIA3-003 43746410-43756725 processed_transcript
  ENST00000497349 PDIA3-007 43770283-43771545 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000300289ENST00000434494ENST00000469684ENST00000497349
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000300289 N/A N/A N/A N/A 44.166±28.29
ENST00000434494 216.569±0.00 181.210±69.86 66.085±0.00 215.304±0.00 196.044±180.76
ENST00000469684 N/A N/A N/A N/A 11.968±0.00
ENST00000497349 575.392±0.00 N/A 474.667±0.00 N/A 290.332±47.46

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007WI CIL_0007WI_0001 VISTA
CIL_00067X CIL_00067X_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0003756 IBA protein disulfide isomerase activity
GO:0004197 TAS cysteine-type endopeptidase activity
GO:0004629 TAS phospholipase C activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005783 IDA:IEA endoplasmic reticulum
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005790 IEA smooth endoplasmic reticulum
GO:0005925 IDA focal adhesion
GO:0006457 IBA protein folding
GO:0006508 TAS proteolysis
GO:0006606 TAS protein import into nucleus
GO:0006621 TAS protein retention in ER lumen
GO:0006662 IEA glycerol ether metabolic process
GO:0007165 TAS signal transduction
GO:0009986 IDA cell surface
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0016853 IEA isomerase activity
GO:0018279 TAS protein N-linked glycosylation via asparagine
GO:0034976 IBA response to endoplasmic reticulum stress
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0045454 IEA cell redox homeostasis
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:2001238 IEA positive regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027248 Pdia3 protein_coding Mus_musculus

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