ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: prohibitin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167085 PHB 9606 - 17:49404049-49414905 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300408 PHB-001 49404052-49414880 protein_coding
  ENST00000393345 PHB-004 49408756-49414858 retained_intron
  ENST00000419140 PHB-002 49405073-49414884 protein_coding
  ENST00000434917 PHB-007 49409350-49414876 protein_coding
  ENST00000446735 PHB-003 49406761-49414848 protein_coding
  ENST00000504124 PHB-009 49405161-49414858 protein_coding
  ENST00000506273 PHB-015 49409076-49414877 processed_transcript
  ENST00000507748 PHB-014 49409449-49412234 retained_intron
  ENST00000508009 PHB-013 49405187-49413253 processed_transcript
  ENST00000511832 PHB-201 49404049-49414905 protein_coding
  ENST00000511933 PHB-016 49405068-49407473 retained_intron
  ENST00000512041 PHB-010 49406759-49414802 protein_coding
  ENST00000513412 PHB-011 49412686-49414878 retained_intron
  ENST00000614445 PHB-202 49404049-49414905 protein_coding
  ENST00000617874 PHB-203 49404049-49414858 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000300408ENST00000393345ENST00000419140ENST00000504124ENST00000506273ENST00000511832ENST00000512041
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000300408 N/A 3.975±0.31 N/A N/A 11.805±7.16
ENST00000393345 N/A N/A N/A N/A 30.426±22.24
ENST00000419140 198.301±0.93 12.109±1.37 14.615±0.00 30.933±0.00 40.461±26.90
ENST00000504124 N/A 84.758±27.54 N/A N/A 37.081±24.68
ENST00000506273 N/A 122.015±17.37 N/A 69.924±0.00 2.688±0.00
ENST00000511832 N/A 18.095±9.03 N/A N/A 15.642±10.94
ENST00000512041 N/A N/A N/A 51.766±0.00 38.718±24.24

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IEA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001649 IDA osteoblast differentiation
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 TAS mitochondrial inner membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0008285 IMP negative regulation of cell proliferation
GO:0010944 IDA negative regulation of transcription by competitive promoter binding
GO:0016020 IDA membrane
GO:0016575 IDA histone deacetylation
GO:0019899 IPI enzyme binding
GO:0030308 IMP negative regulation of cell growth
GO:0042826 IPI histone deacetylase binding
GO:0042981 TAS regulation of apoptotic process
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0050847 IDA progesterone receptor signaling pathway
GO:0060766 IDA negative regulation of androgen receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome
GO:0071354 IDA cellular response to interleukin-6
GO:0071897 IEA DNA biosynthetic process
GO:2000323 IDA negative regulation of glucocorticoid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057414 phb protein_coding Danio_rerio
ENSMUSG00000038845 Phb protein_coding Mus_musculus

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