ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pyruvate dehydrogenase (lipoamide) beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168291 PDHB 9606 - 3:58427630-58433857 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302746 PDHB-001 58427630-58433852 protein_coding
  ENST00000383714 PDHB-008 58427630-58433857 protein_coding
  ENST00000461692 PDHB-002 58427692-58433839 retained_intron
  ENST00000469364 PDHB-006 58427651-58433820 nonsense_mediated_decay
  ENST00000469827 PDHB-009 58431432-58433829 retained_intron
  ENST00000474765 PDHB-007 58427683-58433814 protein_coding
  ENST00000479945 PDHB-003 58427681-58433816 retained_intron
  ENST00000480626 PDHB-011 58430210-58433818 retained_intron
  ENST00000482894 PDHB-010 58431334-58433828 retained_intron
  ENST00000485460 PDHB-005 58427672-58433818 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000302746ENST00000383714ENST00000469827ENST00000479945ENST00000480626ENST00000482894ENST00000485460
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000302746 22.424±7.50 19.056±4.10 N/A 43.434±0.00 26.401±9.96
ENST00000383714 2.992±0.00 N/A 15.728±0.00 N/A N/A
ENST00000469827 N/A N/A N/A N/A 25.950±4.78
ENST00000479945 N/A N/A N/A N/A 1.435±0.58
ENST00000480626 N/A 16.751±0.62 N/A N/A 5.243±0.06
ENST00000482894 N/A N/A N/A N/A 28.985±5.70
ENST00000485460 N/A 12.605±2.89 13.421±0.00 N/A 9.941±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002QD CIL_0002QD_0002 CGP
CIL_0002QQ CIL_0002QQ_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004738 IDA pyruvate dehydrogenase activity
GO:0004739 IEA pyruvate dehydrogenase (acetyl-transferring) activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006006 IEA glucose metabolic process
GO:0006086 IDA acetyl-CoA biosynthetic process from pyruvate
GO:0006090 TAS pyruvate metabolic process
GO:0006099 IDA tricarboxylic acid cycle
GO:0008152 IEA metabolic process
GO:0010510 TAS regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045254 IDA pyruvate dehydrogenase complex
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021346 pdhb protein_coding Danio_rerio
ENSMUSG00000021748 Pdhb protein_coding Mus_musculus

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