ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168394 TAP1 9606 - 6:32845209-32853978 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354258 TAP1-001 32845209-32853978 protein_coding
  ENST00000486332 TAP1-002 32845209-32850142 retained_intron
  ENST00000487296 TAP1-003 32845675-32848230 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000354258
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000354258 16.127±0.00 12.323±4.34 63.650±0.00 19.313±17.58

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000423 CIL_000423_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005739 IEA mitochondrion
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0006952 IEA defense response
GO:0015197 IMP peptide transporter activity
GO:0015440 IEA peptide-transporting ATPase activity
GO:0015833 IMP peptide transport
GO:0016020 IDA membrane
GO:0016021 IDA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0019060 IMP intracellular transport of viral protein in host cell
GO:0019885 IMP:IEA antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 IPI MHC class Ib protein binding
GO:0030176 IDA:IEA integral component of endoplasmic reticulum membrane
GO:0042287 IEA MHC protein binding
GO:0042288 IEA MHC class I protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042605 NAS peptide antigen binding
GO:0042626 IBA:IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042803 ISS protein homodimerization activity
GO:0042825 IDA:IEA TAP complex
GO:0043531 IDA ADP binding
GO:0046967 IMP cytosol to ER transport
GO:0046978 ISS TAP1 binding
GO:0046979 IPI TAP2 binding
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079766 tap1 protein_coding Danio_rerio
ENSMUSG00000037321 Tap1 protein_coding Mus_musculus

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