ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: microtubule crosslinking factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168502 MTCL1 9606 + 18:8705661-8832778 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000306329 MTCL1-015 8705661-8828946 protein_coding
  ENST00000359865 MTCL1-001 8717371-8832778 protein_coding
  ENST00000400050 MTCL1-201 8717898-8832777 protein_coding
  ENST00000517554 MTCL1-005 8784658-8787303 retained_intron
  ENST00000517570 MTCL1-003 8707411-8832777 protein_coding
  ENST00000518226 MTCL1-012 8809818-8813157 processed_transcript
  ENST00000518815 MTCL1-006 8789674-8832778 protein_coding
  ENST00000519823 MTCL1-017 8811131-8819245 processed_transcript
  ENST00000520495 MTCL1-004 8782088-8810002 nonsense_mediated_decay
  ENST00000520926 MTCL1-013 8812845-8819171 retained_intron
  ENST00000521018 MTCL1-010 8784674-8787344 processed_transcript
  ENST00000522146 MTCL1-008 8717376-8777977 retained_intron
  ENST00000522592 MTCL1-011 8800442-8813044 processed_transcript
  ENST00000523122 MTCL1-007 8717759-8718592 protein_coding
  ENST00000523811 MTCL1-009 8784541-8785860 processed_transcript
  ENST00000581670 MTCL1-016 8829923-8832778 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000306329ENST00000400050ENST00000517570ENST00000518815ENST00000522146ENST00000581670
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000306329 N/A 2.906±1.05 N/A 0.805±0.00 1.754±1.28
ENST00000400050 N/A 1.962±0.23 N/A N/A N/A
ENST00000517570 N/A 3.090±0.94 N/A N/A 1.068±0.58
ENST00000518815 N/A 3.059±0.90 N/A N/A 2.756±0.98
ENST00000522146 N/A N/A N/A N/A 4.571±0.00
ENST00000581670 1.328±0.15 N/A 1.470±0.00 N/A 2.490±1.92

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00025R CIL_00025R_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000922 IDA spindle pole
GO:0001578 ISS microtubule bundle formation
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005856 IDA cytoskeleton
GO:0008017 IDA microtubule binding
GO:0010506 IEA regulation of autophagy
GO:0016327 ISS apicolateral plasma membrane
GO:0016328 ISS lateral plasma membrane
GO:0030496 IDA midbody
GO:0042803 ISS protein homodimerization activity
GO:0044822 IDA poly(A) RNA binding
GO:0045197 ISS establishment or maintenance of epithelial cell apical/basal polarity
GO:0090314 ISS positive regulation of protein targeting to membrane
GO:0097427 ISS microtubule bundle
GO:2000576 ISS positive regulation of microtubule motor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091408 MTCL1 protein_coding Danio_rerio
ENSMUSG00000052105 Mtcl1 protein_coding Mus_musculus

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