ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: salt-inducible kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170145 SIK2 9606 + 11:111602391-111730853 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304987 SIK2-001 111602391-111730853 protein_coding
  ENST00000533868 SIK2-003 111718742-111720674 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000304987
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000304987 0.668±0.00 5.362±1.99 1.181±0.00 3.278±0.00 4.312±1.88

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA:IEA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0006468 IDA:IEA protein phosphorylation
GO:0008286 IEA insulin receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IDA:IEA intracellular signal transduction
GO:0046626 ISS regulation of insulin receptor signaling pathway
GO:0046777 IDA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062315 sik2b protein_coding Danio_rerio
ENSDARG00000079618 sik2a protein_coding Danio_rerio
ENSMUSG00000037112 Sik2 protein_coding Mus_musculus

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