ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: keratin 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170421 KRT8 9606 - 12:52897187-52949954 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000293308 KRT8-002 52897194-52905072 protein_coding
  ENST00000546542 KRT8-015 52904676-52907060 protein_coding
  ENST00000546583 KRT8-005 52897208-52905052 retained_intron
  ENST00000546826 KRT8-013 52899935-52949882 protein_coding
  ENST00000546897 KRT8-003 52897281-52949824 protein_coding
  ENST00000546900 KRT8-017 52900588-52903648 protein_coding
  ENST00000546921 KRT8-009 52949216-52949954 retained_intron
  ENST00000547031 KRT8-020 52898469-52901867 retained_intron
  ENST00000547176 KRT8-019 52899996-52901947 nonsense_mediated_decay
  ENST00000547413 KRT8-016 52901864-52906618 protein_coding
  ENST00000548998 KRT8-014 52900008-52949776 protein_coding
  ENST00000549176 KRT8-018 52899794-52902204 retained_intron
  ENST00000549198 KRT8-012 52948484-52949831 processed_transcript
  ENST00000550170 KRT8-008 52897216-52905044 retained_intron
  ENST00000551318 KRT8-010 52948651-52949920 processed_transcript
  ENST00000552150 KRT8-004 52897297-52926469 protein_coding
  ENST00000552551 KRT8-001 52897187-52949842 protein_coding
  ENST00000552877 KRT8-011 52948650-52949874 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HHSECHUVECENST00000293308ENST00000552551
Transcript ID HHSEC HUVEC
ENST00000293308 8.158±0.00 28.364±5.44
ENST00000552551 N/A 6.480±5.23

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00038V CIL_00038V_0001 CGP
CIL_0006T8 CIL_0006T8_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005882 IDA:IEA intermediate filament
GO:0005911 IEA cell-cell junction
GO:0016010 IEA dystrophin-associated glycoprotein complex
GO:0016032 IEA viral process
GO:0030018 IEA Z disc
GO:0032403 IEA protein complex binding
GO:0033209 IEA tumor necrosis factor-mediated signaling pathway
GO:0042383 IEA sarcolemma
GO:0043034 IEA costamere
GO:0045095 IEA keratin filament
GO:0045214 IEA sarcomere organization
GO:0051599 IEA response to hydrostatic pressure
GO:0051707 IEA response to other organism
GO:0060706 IEA cell differentiation involved in embryonic placenta development
GO:0070062 IDA extracellular vesicular exosome
GO:0071944 IEA cell periphery
GO:0097110 IPI scaffold protein binding
GO:0097191 IEA extrinsic apoptotic signaling pathway
GO:0097284 IEA hepatocyte apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017624 krt4 protein_coding Danio_rerio
ENSDARG00000043242 si:dkey-222f2.1 protein_coding Danio_rerio
ENSDARG00000058358 krt8 protein_coding Danio_rerio
ENSDARG00000058371 krt5 protein_coding Danio_rerio
ENSDARG00000058462 zgc:158846 protein_coding Danio_rerio
ENSMUSG00000049382 Krt8 protein_coding Mus_musculus

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