ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170836 PPM1D 9606 + 17:60600183-60666280 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305921 PPM1D-001 60600183-60666280 protein_coding
  ENST00000392995 PPM1D-002 60600269-60664473 nonsense_mediated_decay
  ENST00000590418 PPM1D-004 60604594-60633957 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000305921ENST00000392995
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000305921 1.323±0.00 1.524±0.51 0.989±0.00 0.600±0.00 2.316±0.93
ENST00000392995 0.516±0.09 4.579±0.96 4.058±0.00 3.728±0.00 4.406±3.75

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000704 CIL_000704_0001 CGP
CIL_000569 CIL_000569_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IEA G2/M transition of mitotic cell cycle
GO:0003824 IEA catalytic activity
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0006470 TAS protein dephosphorylation
GO:0008152 IEA metabolic process
GO:0008285 TAS negative regulation of cell proliferation
GO:0009314 TAS response to radiation
GO:0009617 IEA response to bacterium
GO:0035970 IDA peptidyl-threonine dephosphorylation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009273 ppm1da protein_coding Danio_rerio
ENSDARG00000021380 ppm1db protein_coding Danio_rerio
ENSMUSG00000020525 Ppm1d protein_coding Mus_musculus

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