ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: cofilin 1 (non-muscle)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172757 CFL1 9606 - 11:65823022-65862026 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308162 CFL1-201 65854837-65858333 protein_coding
  ENST00000524553 CFL1-014 65855054-65856964 protein_coding
  ENST00000525451 CFL1-001 65854675-65859415 protein_coding
  ENST00000525710 CFL1-010 65826322-65831770 processed_transcript
  ENST00000526975 CFL1-008 65855974-65859282 protein_coding
  ENST00000527344 CFL1-013 65854975-65857033 protein_coding
  ENST00000527752 CFL1-009 65823022-65858157 processed_transcript
  ENST00000530157 CFL1-011 65823022-65824103 processed_transcript
  ENST00000530413 CFL1-015 65855418-65856473 protein_coding
  ENST00000530945 CFL1-003 65854832-65858194 retained_intron
  ENST00000531407 CFL1-002 65855009-65857868 protein_coding
  ENST00000531413 CFL1-007 65855257-65859289 protein_coding
  ENST00000532134 CFL1-005 65855358-65862026 protein_coding
  ENST00000534769 CFL1-006 65855241-65861421 protein_coding
  ENST00000534784 CFL1-012 65855957-65857543 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000308162ENST00000525451ENST00000526975ENST00000530945ENST00000531413
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000308162 1075.935±311.92 848.431±296.12 625.068±0.00 790.475±0.00 636.105±344.26
ENST00000525451 N/A N/A N/A N/A 244.980±59.69
ENST00000526975 N/A 344.868±0.00 N/A N/A 1575.490±209.93
ENST00000530945 N/A N/A N/A N/A 8.331±3.32
ENST00000531413 N/A 708.709±121.16 N/A 432.028±0.00 333.020±244.29

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002MN CIL_0002MN_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000281 IEA mitotic cytokinesis
GO:0001755 IEA neural crest cell migration
GO:0001842 IEA neural fold formation
GO:0002576 TAS platelet degranulation
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005886 IEA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006468 IEA protein phosphorylation
GO:0006606 IEA protein import into nucleus
GO:0006928 IEA cellular component movement
GO:0007010 IMP cytoskeleton organization
GO:0007015 IEA actin filament organization
GO:0007266 TAS Rho protein signal transduction
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0009615 IEP response to virus
GO:0015629 IEA actin cytoskeleton
GO:0016020 IDA membrane
GO:0022604 IMP regulation of cell morphogenesis
GO:0030010 IEA establishment of cell polarity
GO:0030027 IEA lamellipodium
GO:0030030 IEA cell projection organization
GO:0030036 TAS actin cytoskeleton organization
GO:0030042 IEA actin filament depolymerization
GO:0030168 TAS platelet activation
GO:0030836 IEA positive regulation of actin filament depolymerization
GO:0030864 IEA cortical actin cytoskeleton
GO:0031252 IEA cell leading edge
GO:0031982 IDA vesicle
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043066 TAS negative regulation of apoptotic process
GO:0043200 IEA response to amino acid
GO:0045087 TAS innate immune response
GO:0045792 IEA negative regulation of cell size
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021124 cfl1 protein_coding Danio_rerio
ENSMUSG00000056201 Cfl1 protein_coding Mus_musculus

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