ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pyruvate dehyrogenase phosphatase catalytic subunit 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172840 PDP2 9606 + 16:66878589-66895754 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311765 PDP2-001 66880361-66891096 protein_coding
  ENST00000561704 PDP2-009 66880519-66884594 protein_coding
  ENST00000566543 PDP2-002 66878589-66884739 protein_coding
  ENST00000566776 PDP2-005 66880607-66885011 protein_coding
  ENST00000566805 PDP2-004 66880549-66893000 nonsense_mediated_decay
  ENST00000568398 PDP2-003 66880531-66884366 protein_coding
  ENST00000568720 PDP2-008 66880582-66895754 processed_transcript
  ENST00000568869 PDP2-006 66880515-66884749 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000311765ENST00000566776
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000311765 0.584±0.10 0.857±0.00 1.040±0.80
ENST00000566776 N/A N/A 1.847±1.59

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007WN CIL_0007WN_0001 VISTA
CIL_0004GC CIL_0004GC_0001 CGP
CIL_0004IP CIL_0004IP_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0004724 IEA magnesium-dependent protein serine/threonine phosphatase activity
GO:0004741 IEA [pyruvate dehydrogenase (lipoamide)] phosphatase activity
GO:0005739 IEA mitochondrion
GO:0005759 TAS mitochondrial matrix
GO:0006090 TAS pyruvate metabolic process
GO:0006470 IEA protein dephosphorylation
GO:0010510 TAS regulation of acetyl-CoA biosynthetic process from pyruvate
GO:0035970 IEA peptidyl-threonine dephosphorylation
GO:0044237 TAS cellular metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058571 pdp2 protein_coding Danio_rerio
ENSMUSG00000048371 Pdp2 protein_coding Mus_musculus

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