ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: adenylate cyclase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173175 ADCY5 9606 - 3:123282296-123449758 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309879 ADCY5-003 123284578-123416342 protein_coding
  ENST00000462833 ADCY5-001 123282296-123449758 protein_coding
  ENST00000466617 ADCY5-004 123300220-123404561 protein_coding
  ENST00000468683 ADCY5-008 123300251-123318152 retained_intron
  ENST00000470367 ADCY5-006 123352450-123419209 processed_transcript
  ENST00000474577 ADCY5-010 123297257-123304079 retained_intron
  ENST00000476455 ADCY5-007 123332595-123404283 nonsense_mediated_decay
  ENST00000478092 ADCY5-011 123284446-123287111 retained_intron
  ENST00000483566 ADCY5-005 123330940-123420274 protein_coding
  ENST00000491190 ADCY5-002 123283944-123419209 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000309879ENST00000462833ENST00000466617ENST00000468683ENST00000470367ENST00000478092ENST00000483566ENST00000491190
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000309879 N/A 0.300±0.11 N/A N/A N/A
ENST00000462833 0.010±0.00 0.131±0.09 0.076±0.00 0.049±0.00 0.016±0.01
ENST00000466617 N/A N/A N/A N/A 0.044±0.04
ENST00000468683 N/A N/A N/A N/A 0.118±0.00
ENST00000470367 0.096±0.00 N/A N/A N/A N/A
ENST00000478092 N/A N/A 0.162±0.00 0.140±0.00 0.105±0.08
ENST00000483566 N/A N/A N/A N/A 0.076±0.01
ENST00000491190 N/A 0.023±0.00 N/A 0.031±0.00 0.007±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00007A CIL_00007A_0002 CGP
CIL_000075 CIL_000075_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001973 IEA adenosine receptor signaling pathway
GO:0004016 IEA adenylate cyclase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005886 ISS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0006171 IEA cAMP biosynthetic process
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007191 IEA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007193 TAS adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007195 IEA adenylate cyclase-inhibiting dopamine receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007268 TAS synaptic transmission
GO:0007626 IEA locomotory behavior
GO:0008179 ISS adenylate cyclase binding
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009190 IEA cyclic nucleotide biosynthetic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016849 IEA phosphorus-oxygen lyase activity
GO:0034199 TAS activation of protein kinase A activity
GO:0035556 IEA intracellular signal transduction
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0046872 IEA metal ion binding
GO:0046982 ISS protein heterodimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050885 IEA neuromuscular process controlling balance
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:0072372 ISS primary cilium

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087748 CABZ01112027.1 protein_coding Danio_rerio
ENSDARG00000091342 adcy5 protein_coding Danio_rerio
ENSMUSG00000022840 Adcy5 protein_coding Mus_musculus

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