ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: glutaredoxin (thioltransferase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173221 GLRX 9606 - 5:95751319-95823005 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000237858 GLRX-001 95813849-95823005 protein_coding
  ENST00000379979 GLRX-002 95813971-95822714 protein_coding
  ENST00000505427 GLRX-004 95814563-95822722 protein_coding
  ENST00000507412 GLRX-003 95813979-95819502 retained_intron
  ENST00000507605 GLRX-006 95781336-95822291 processed_transcript
  ENST00000508780 GLRX-007 95751319-95822726 protein_coding
  ENST00000512469 GLRX-005 95816410-95822711 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000237858ENST00000379979ENST00000505427ENST00000507412ENST00000507605ENST00000508780ENST00000512469
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000237858 25.004±4.38 22.178±14.32 9.056±0.00 11.877±0.00 8.639±3.56
ENST00000379979 N/A 5.196±3.43 2.343±0.00 N/A 2.408±1.56
ENST00000505427 N/A N/A N/A N/A 1.579±0.00
ENST00000507412 N/A 0.182±0.00 N/A N/A 0.606±0.43
ENST00000507605 N/A 0.382±0.04 N/A N/A 0.182±0.00
ENST00000508780 N/A N/A N/A N/A 14.815±7.99
ENST00000512469 20.334±0.00 26.222±16.11 N/A 32.300±0.00 22.680±9.01

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0009055 IEA electron carrier activity
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0015038 TAS glutathione disulfide oxidoreductase activity
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0044281 TAS small molecule metabolic process
GO:0045454 IEA cell redox homeostasis
GO:0045838 IDA positive regulation of membrane potential
GO:0047485 IPI protein N-terminus binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0080058 TAS protein deglutathionylation
GO:0097573 TAS glutathione oxidoreductase activity
GO:2000651 IDA positive regulation of sodium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028106 glrx protein_coding Danio_rerio
ENSMUSG00000021591 Glrx protein_coding Mus_musculus

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