ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dystroglycan 1 (dystrophin-associated glycoprotein 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173402 DAG1 9606 + 3:49468703-49535618 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308775 DAG1-001 49470132-49535615 protein_coding
  ENST00000418588 DAG1-004 49470136-49510799 protein_coding
  ENST00000419218 DAG1-011 49470316-49510580 protein_coding
  ENST00000421560 DAG1-003 49470132-49530831 protein_coding
  ENST00000428779 DAG1-009 49470300-49510821 protein_coding
  ENST00000430636 DAG1-012 49470319-49510560 protein_coding
  ENST00000431960 DAG1-015 49470247-49530864 protein_coding
  ENST00000435508 DAG1-005 49470277-49510765 protein_coding
  ENST00000452060 DAG1-007 49470279-49510794 protein_coding
  ENST00000452317 DAG1-006 49470277-49510657 protein_coding
  ENST00000461492 DAG1-010 49470306-49531211 processed_transcript
  ENST00000461987 DAG1-017 49470302-49487415 processed_transcript
  ENST00000466701 DAG1-008 49470289-49510490 processed_transcript
  ENST00000469139 DAG1-002 49468713-49510636 processed_transcript
  ENST00000475424 DAG1-016 49492716-49510741 processed_transcript
  ENST00000479935 DAG1-018 49510224-49530911 processed_transcript
  ENST00000496474 DAG1-014 49470354-49510516 processed_transcript
  ENST00000515359 DAG1-201 49468703-49535618 protein_coding
  ENST00000538711 DAG1-202 49470132-49535618 protein_coding
  ENST00000539901 DAG1-203 49470132-49535618 protein_coding
  ENST00000541308 DAG1-204 49470132-49535618 protein_coding
  ENST00000545947 DAG1-205 49470132-49535618 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000308775ENST00000515359ENST00000538711
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000308775 12.415±6.45 N/A 6.978±0.00 8.367±4.69
ENST00000515359 N/A 0.518±0.00 N/A 1.311±1.11
ENST00000538711 N/A N/A N/A 3.678±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001618 IEA virus receptor activity
GO:0002011 IEA morphogenesis of an epithelial sheet
GO:0002162 IEA dystroglycan binding
GO:0003779 IDA actin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005604 IDA basement membrane
GO:0005615 IDA extracellular space
GO:0005654 IDA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005913 IEA cell-cell adherens junction
GO:0005925 IDA focal adhesion
GO:0006509 IDA membrane protein ectodomain proteolysis
GO:0006607 IDA NLS-bearing protein import into nucleus
GO:0007016 IMP:IEA cytoskeletal anchoring at plasma membrane
GO:0008307 IMP structural constituent of muscle
GO:0009279 IEA cell outer membrane
GO:0009615 IEA response to virus
GO:0014044 IEA Schwann cell development
GO:0015631 IDA tubulin binding
GO:0016010 IDA:IEA dystrophin-associated glycoprotein complex
GO:0016011 IEA dystroglycan complex
GO:0016020 IEA membrane
GO:0016021 IDA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0016340 IEA calcium-dependent cell-matrix adhesion
GO:0017166 IPI vinculin binding
GO:0019048 IDA modulation by virus of host morphology or physiology
GO:0021682 IEA nerve maturation
GO:0022011 IEA myelination in peripheral nervous system
GO:0030027 IDA lamellipodium
GO:0030175 IDA filopodium
GO:0030198 TAS extracellular matrix organization
GO:0030336 IMP negative regulation of cell migration
GO:0032403 IEA protein complex binding
GO:0033268 IEA node of Ranvier
GO:0034453 IMP microtubule anchoring
GO:0042169 IDA SH2 domain binding
GO:0042383 IEA sarcolemma
GO:0043034 IEA costamere
GO:0043237 ISS laminin-1 binding
GO:0043409 IMP negative regulation of MAPK cascade
GO:0043434 IEA response to peptide hormone
GO:0045121 IEA membrane raft
GO:0045211 IEA postsynaptic membrane
GO:0051393 IDA alpha-actinin binding
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0060441 IEA epithelial tube branching involved in lung morphogenesis
GO:0060445 IEA branching involved in salivary gland morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:0070938 IDA contractile ring
GO:0071679 IEA commissural neuron axon guidance
GO:0071711 IEA basement membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016153 dag1 protein_coding Danio_rerio
ENSMUSG00000039952 Dag1 protein_coding Mus_musculus

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