ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: protein tyrosine phosphatase, receptor type, M
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173482 PTPRM 9606 + 18:7566782-8406861 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332175 PTPRM-001 7566782-8406861 protein_coding
  ENST00000400053 PTPRM-003 7754973-8406856 protein_coding
  ENST00000400060 PTPRM-201 7774140-8406858 protein_coding
  ENST00000577468 PTPRM-010 8113571-8296455 protein_coding
  ENST00000577827 PTPRM-013 8121852-8406666 retained_intron
  ENST00000578093 PTPRM-009 8244057-8251821 processed_transcript
  ENST00000578571 PTPRM-006 8017823-8113632 processed_transcript
  ENST00000578600 PTPRM-005 8017792-8069959 processed_transcript
  ENST00000578698 PTPRM-007 8049364-8076564 processed_transcript
  ENST00000578916 PTPRM-004 7946870-8069712 protein_coding
  ENST00000580170 PTPRM-012 7566782-8406668 protein_coding
  ENST00000580838 PTPRM-015 8247874-8270447 processed_transcript
  ENST00000580949 PTPRM-017 8399701-8406664 processed_transcript
  ENST00000583153 PTPRM-016 8370933-8379313 protein_coding
  ENST00000583289 PTPRM-008 8085702-8143778 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000332175ENST00000400053ENST00000400060ENST00000577827ENST00000578916ENST00000580170ENST00000580949
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000332175 0.701±0.00 4.479±3.55 N/A N/A 5.813±4.39
ENST00000400053 N/A N/A N/A N/A 3.124±3.03
ENST00000400060 0.941±0.00 7.755±1.67 N/A 2.576±0.00 9.083±2.71
ENST00000577827 N/A N/A 2.135±0.00 N/A 3.913±0.28
ENST00000578916 N/A N/A N/A N/A 0.364±0.00
ENST00000580170 N/A N/A N/A N/A 0.631±0.00
ENST00000580949 18.749±1.48 N/A 53.422±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001937 IMP negative regulation of endothelial cell proliferation
GO:0004725 IEA:IDA protein tyrosine phosphatase activity
GO:0005001 IDA transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005887 NAS integral component of plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005913 IDA cell-cell adherens junction
GO:0006470 IDA:IEA protein dephosphorylation
GO:0007156 IDA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007165 IDA signal transduction
GO:0010596 IMP negative regulation of endothelial cell migration
GO:0010842 IMP retina layer formation
GO:0016020 IEA membrane
GO:0016311 IEA dephosphorylation
GO:0016525 IMP negative regulation of angiogenesis
GO:0016791 IEA phosphatase activity
GO:0030027 IDA lamellipodium
GO:0031175 IDA neuron projection development
GO:0031290 IDA retinal ganglion cell axon guidance
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042493 IDA response to drug
GO:0042802 IPI identical protein binding
GO:0045296 IDA cadherin binding
GO:0045909 IEA positive regulation of vasodilation
GO:0048471 IDA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089172 PTPRM protein_coding Danio_rerio
ENSMUSG00000033278 Ptprm protein_coding Mus_musculus

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