ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pleckstrin homology-like domain, family A, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174307 PHLDA3 9606 - 1:201464383-201469237 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367309 PHLDA3-002 201465958-201469237 protein_coding
  ENST00000367311 PHLDA3-001 201464383-201469184 protein_coding
  ENST00000485436 PHLDA3-003 201465853-201468581 processed_transcript
  ENST00000497057 PHLDA3-004 201465944-201466657 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000367309ENST00000367311ENST00000485436
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000367309 85.236±3.08 11.035±6.52 N/A 15.247±0.00 18.040±16.03
ENST00000367311 30.078±4.92 8.187±4.41 N/A 10.018±0.00 11.357±10.38
ENST00000485436 N/A 7.348±2.73 1.369±0.00 11.244±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005546 IDA phosphatidylinositol-4,5-bisphosphate binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0009653 TAS anatomical structure morphogenesis
GO:0010314 IDA phosphatidylinositol-5-phosphate binding
GO:0032266 IDA phosphatidylinositol-3-phosphate binding
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043065 IDA positive regulation of apoptotic process
GO:0043325 IDA phosphatidylinositol-3,4-bisphosphate binding
GO:0051898 IDA negative regulation of protein kinase B signaling
GO:0070062 IDA extracellular vesicular exosome
GO:0080025 IDA phosphatidylinositol-3,5-bisphosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037804 phlda3 protein_coding Danio_rerio
ENSMUSG00000041801 Phlda3 protein_coding Mus_musculus

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