ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174437 ATP2A2 9606 + 12:110280756-110351093 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308664 ATP2A2-001 110281116-110351090 protein_coding
  ENST00000313432 ATP2A2-011 110345437-110351093 retained_intron
  ENST00000377685 ATP2A2-002 110281297-110351057 nonsense_mediated_decay
  ENST00000539276 ATP2A2-003 110281681-110347326 protein_coding
  ENST00000547050 ATP2A2-008 110325801-110332632 retained_intron
  ENST00000547792 ATP2A2-010 110343256-110345247 retained_intron
  ENST00000548169 ATP2A2-006 110292049-110346621 protein_coding
  ENST00000549840 ATP2A2-007 110327687-110332143 processed_transcript
  ENST00000550248 ATP2A2-005 110295991-110323072 processed_transcript
  ENST00000550262 ATP2A2-009 110329399-110334291 retained_intron
  ENST00000552636 ATP2A2-004 110280756-110296712 protein_coding
  ENST00000553144 ATP2A2-012 110346201-110350373 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000308664ENST00000313432ENST00000377685ENST00000539276ENST00000548169
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000308664 N/A 11.168±0.00 N/A N/A 6.304±2.78
ENST00000313432 3.645±1.93 7.171±0.00 2.189±0.00 N/A 12.390±8.59
ENST00000377685 3.582±1.05 N/A N/A N/A N/A
ENST00000539276 8.030±0.00 35.672±10.08 3.101±0.00 53.590±0.00 32.762±27.04
ENST00000548169 N/A 25.680±5.34 N/A N/A 20.921±9.13

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001QG CIL_0001QG_0002 CGP
CIL_0001QF CIL_0001QF_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0002026 IEA regulation of the force of heart contraction
GO:0005388 TAS:IEA calcium-transporting ATPase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006810 TAS transport
GO:0006816 IEA calcium ion transport
GO:0006874 TAS cellular calcium ion homeostasis
GO:0006984 IEA ER-nucleus signaling pathway
GO:0007155 TAS cell adhesion
GO:0007596 TAS blood coagulation
GO:0008022 IPI protein C-terminus binding
GO:0008152 IEA metabolic process
GO:0008544 TAS epidermis development
GO:0010460 TAS positive regulation of heart rate
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0019899 IPI enzyme binding
GO:0031095 TAS platelet dense tubular network membrane
GO:0033017 TAS sarcoplasmic reticulum membrane
GO:0034220 TAS ion transmembrane transport
GO:0043231 TAS intracellular membrane-bounded organelle
GO:0044548 IPI S100 protein binding
GO:0045822 IEA negative regulation of heart contraction
GO:0046872 IEA metal ion binding
GO:0055085 TAS transmembrane transport
GO:0055119 TAS relaxation of cardiac muscle
GO:0070296 TAS sarcoplasmic reticulum calcium ion transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0086036 TAS regulation of cardiac muscle cell membrane potential
GO:0086039 TAS calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005122 atp2a2b protein_coding Danio_rerio
ENSDARG00000029439 atp2a2a protein_coding Danio_rerio
ENSMUSG00000029467 Atp2a2 protein_coding Mus_musculus

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