ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ribosomal protein S6 kinase, 70kDa, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175634 RPS6KB2 9606 + 11:67428460-67435408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312629 RPS6KB2-003 67428501-67435408 protein_coding
  ENST00000420069 RPS6KB2-009 67428498-67432995 protein_coding
  ENST00000524814 RPS6KB2-013 67428494-67432981 processed_transcript
  ENST00000524934 RPS6KB2-006 67428494-67431403 protein_coding
  ENST00000525088 RPS6KB2-004 67428505-67435401 retained_intron
  ENST00000525726 RPS6KB2-011 67432240-67432815 retained_intron
  ENST00000525996 RPS6KB2-010 67429527-67435018 nonsense_mediated_decay
  ENST00000526268 RPS6KB2-007 67432776-67434644 retained_intron
  ENST00000528964 RPS6KB2-005 67428504-67435344 nonsense_mediated_decay
  ENST00000530623 RPS6KB2-008 67428460-67431582 retained_intron
  ENST00000531765 RPS6KB2-012 67433444-67434954 retained_intron
  ENST00000556575 RPS6KB2-014 67428483-67432985 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000312629ENST00000524814ENST00000525088ENST00000525996ENST00000526268ENST00000528964ENST00000556575
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000312629 12.673±0.51 5.927±0.77 N/A 5.404±0.00 14.780±11.69
ENST00000524814 N/A 28.047±3.86 N/A N/A 17.905±4.08
ENST00000525088 N/A 0.502±0.01 1.540±0.00 0.749±0.00 1.313±0.92
ENST00000525996 14.938±1.76 15.828±3.43 N/A N/A 13.682±1.64
ENST00000526268 N/A 10.673±1.09 18.867±0.00 N/A N/A
ENST00000528964 4.563±0.00 N/A N/A N/A 3.684±0.41
ENST00000556575 N/A N/A N/A N/A 4.150±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 TAS:IEA protein serine/threonine kinase activity
GO:0004711 IEA ribosomal protein S6 kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006412 TAS translation
GO:0006468 IEA protein phosphorylation
GO:0007165 TAS:IEA signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042277 IEA peptide binding
GO:0043491 IEA protein kinase B signaling
GO:0045087 TAS innate immune response
GO:0045948 IMP positive regulation of translational initiation
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000024830 Rps6kb2 protein_coding Mus_musculus

Loading