ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polymerase (DNA directed), epsilon, catalytic subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177084 POLE 9606 - 12:132623753-132687365 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320574 POLE-001 132623762-132687359 protein_coding
  ENST00000416953 POLE-021 132633971-132636025 retained_intron
  ENST00000434528 POLE-027 132634365-132641378 processed_transcript
  ENST00000441786 POLE-015 132626311-132635992 nonsense_mediated_decay
  ENST00000503265 POLE-016 132649353-132651407 processed_transcript
  ENST00000534922 POLE-024 132624555-132632557 retained_intron
  ENST00000535270 POLE-004 132624690-132687328 protein_coding
  ENST00000535934 POLE-010 132672627-132676498 retained_intron
  ENST00000536445 POLE-014 132649321-132660913 retained_intron
  ENST00000537064 POLE-002 132624263-132687347 nonsense_mediated_decay
  ENST00000538196 POLE-026 132625298-132632416 processed_transcript
  ENST00000539215 POLE-012 132672281-132673641 processed_transcript
  ENST00000539357 POLE-009 132681028-132687365 retained_intron
  ENST00000539618 POLE-008 132680531-132681279 retained_intron
  ENST00000540987 POLE-017 132648546-132649365 retained_intron
  ENST00000541213 POLE-020 132632448-132639169 retained_intron
  ENST00000541627 POLE-007 132623753-132625951 retained_intron
  ENST00000542362 POLE-019 132641374-132642206 retained_intron
  ENST00000544414 POLE-022 132632508-132635985 retained_intron
  ENST00000544692 POLE-003 132624706-132634168 retained_intron
  ENST00000544870 POLE-025 132626267-132636000 nonsense_mediated_decay
  ENST00000545015 POLE-013 132672544-132673233 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000320574ENST00000535270ENST00000537064ENST00000541627
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000320574 5.927±1.64 2.088±0.00 5.161±0.00 4.390±4.04
ENST00000535270 N/A N/A N/A 2.100±1.11
ENST00000537064 N/A N/A N/A 1.049±0.00
ENST00000541627 N/A 19.054±0.00 N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000166 IEA nucleotide binding
GO:0000278 TAS mitotic cell cycle
GO:0000722 TAS telomere maintenance via recombination
GO:0000723 TAS telomere maintenance
GO:0000731 IMP DNA synthesis involved in DNA repair
GO:0001701 IEA in utero embryonic development
GO:0003676 IEA nucleic acid binding
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003887 IMP:IEA DNA-directed DNA polymerase activity
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006260 IMP:IEA DNA replication
GO:0006270 TAS DNA replication initiation
GO:0006281 TAS DNA repair
GO:0006283 TAS transcription-coupled nucleotide-excision repair
GO:0006287 IDA base-excision repair, gap-filling
GO:0006289 TAS nucleotide-excision repair
GO:0006297 IMP nucleotide-excision repair, DNA gap filling
GO:0008270 IEA zinc ion binding
GO:0008622 IDA epsilon DNA polymerase complex
GO:0032201 TAS telomere maintenance via semi-conservative replication
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058533 pole protein_coding Danio_rerio
ENSMUSG00000007080 Pole protein_coding Mus_musculus

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