ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: anoctamin 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177119 ANO6 9606 + 12:45215987-45440404 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320560 ANO6-001 45216120-45432351 protein_coding
  ENST00000423947 ANO6-005 45216085-45431782 protein_coding
  ENST00000425752 ANO6-002 45216020-45440404 protein_coding
  ENST00000426898 ANO6-006 45215987-45421217 processed_transcript
  ENST00000441606 ANO6-003 45292683-45432351 protein_coding
  ENST00000550630 ANO6-004 45216120-45313512 nonsense_mediated_decay
  ENST00000551667 ANO6-007 45335549-45347508 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000320560ENST00000423947ENST00000426898ENST00000441606
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000320560 3.423±0.00 13.563±2.27 24.569±0.00 16.513±11.72
ENST00000423947 N/A 4.166±2.92 5.074±0.00 3.855±3.00
ENST00000426898 N/A N/A N/A 0.268±0.00
ENST00000441606 2.734±0.47 N/A N/A 5.988±3.73

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002407 IEA dendritic cell chemotaxis
GO:0002543 IMP activation of blood coagulation via clotting cascade
GO:0005227 ISS calcium activated cation channel activity
GO:0005229 IMP intracellular calcium activated chloride channel activity
GO:0005244 ISS voltage-gated ion channel activity
GO:0005247 IMP voltage-gated chloride channel activity
GO:0005622 IDA intracellular
GO:0005886 IDA plasma membrane
GO:0006812 IDA cation transport
GO:0006821 IMP chloride transport
GO:0007596 ISS blood coagulation
GO:0009986 IDA cell surface
GO:0016020 IDA membrane
GO:0017121 ISS phospholipid scrambling
GO:0017128 IEA phospholipid scramblase activity
GO:0034220 TAS ion transmembrane transport
GO:0034707 IDA chloride channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035630 IEA bone mineralization involved in bone maturation
GO:0042803 IEA protein homodimerization activity
GO:0044070 IMP regulation of anion transport
GO:0055085 TAS transmembrane transport
GO:0061588 IEA calcium activated phospholipid scrambling
GO:0061589 IEA calcium activated phosphatidylserine scrambling
GO:0061590 IEA calcium activated phosphatidylcholine scrambling
GO:0061591 IEA calcium activated galactosylceramide scrambling
GO:0070062 IDA extracellular vesicular exosome
GO:0097045 IMP phosphatidylserine exposure on blood platelet
GO:0098655 ISS cation transmembrane transport
GO:1902476 IEA chloride transmembrane transport
GO:2000353 IMP positive regulation of endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061544 ano6 protein_coding Danio_rerio
ENSMUSG00000064210 Ano6 protein_coding Mus_musculus

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