ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: pseudouridylate synthase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177192 PUS1 9606 + 12:131929200-131945896 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322060 PUS1-003 131929242-131941983 protein_coding
  ENST00000376649 PUS1-001 131929223-131945896 protein_coding
  ENST00000443358 PUS1-002 131929200-131943859 protein_coding
  ENST00000456665 PUS1-008 131929307-131932833 protein_coding
  ENST00000535067 PUS1-010 131929755-131943857 protein_coding
  ENST00000537484 PUS1-007 131929765-131941422 protein_coding
  ENST00000538037 PUS1-005 131929282-131939275 protein_coding
  ENST00000542167 PUS1-004 131929276-131943859 protein_coding
  ENST00000543754 PUS1-011 131940927-131943859 retained_intron
  ENST00000544213 PUS1-009 131929589-131932833 protein_coding
  ENST00000544662 PUS1-006 131929304-131932680 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000322060ENST00000376649ENST00000443358ENST00000542167ENST00000543754ENST00000544213ENST00000544662
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000322060 N/A 6.217±2.06 N/A 10.849±0.00 5.603±2.98
ENST00000376649 N/A 1.528±0.62 1.243±0.00 1.501±0.00 1.669±1.04
ENST00000443358 22.326±5.32 11.813±5.59 5.643±0.00 7.117±0.00 5.647±3.23
ENST00000542167 N/A 1.322±0.00 N/A N/A 1.988±1.84
ENST00000543754 28.314±7.70 4.607±0.46 22.497±0.00 N/A 3.959±2.09
ENST00000544213 N/A N/A N/A N/A 5.281±0.81
ENST00000544662 N/A N/A N/A N/A 1.339±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IEA nuclear chromatin
GO:0001522 IEA pseudouridine synthesis
GO:0003723 IEA RNA binding
GO:0004730 NAS pseudouridylate synthase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0005730 IEA nucleolus
GO:0005739 IEA mitochondrion
GO:0008033 IEA tRNA processing
GO:0009451 IEA RNA modification
GO:0009982 IEA pseudouridine synthase activity
GO:0030374 IEA ligand-dependent nuclear receptor transcription coactivator activity
GO:0031119 IEA tRNA pseudouridine synthesis
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045562 pus1 protein_coding Danio_rerio
ENSMUSG00000029507 Pus1 protein_coding Mus_musculus

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