ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: plectin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178209 PLEC 9606 - 8:143915147-143976734 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322810 PLEC-001 143915153-143950876 protein_coding
  ENST00000345136 PLEC-004 143915147-143939590 protein_coding
  ENST00000354589 PLEC-005 143915153-143943958 protein_coding
  ENST00000354958 PLEC-008 143915153-143953920 protein_coding
  ENST00000356346 PLEC-009 143915153-143973529 protein_coding
  ENST00000357649 PLEC-006 143915153-143942524 protein_coding
  ENST00000398774 PLEC-007 143915153-143944737 protein_coding
  ENST00000436759 PLEC-002 143915153-143976734 protein_coding
  ENST00000526416 PLEC-015 143935277-143946405 protein_coding
  ENST00000527096 PLEC-003 143916177-143975369 protein_coding
  ENST00000527303 PLEC-016 143921932-143927011 protein_coding
  ENST00000527816 PLEC-014 143935918-143946547 protein_coding
  ENST00000528025 PLEC-010 143932400-143975375 protein_coding
  ENST00000528131 PLEC-013 143935979-143958799 protein_coding
  ENST00000532346 PLEC-012 143937664-143975219 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000322810ENST00000345136ENST00000354958ENST00000356346ENST00000357649ENST00000398774ENST00000436759ENST00000527096
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000322810 N/A 13.937±5.35 12.843±0.00 14.423±7.39
ENST00000345136 16.780±0.00 33.014±16.59 32.319±0.00 20.777±13.54
ENST00000354958 N/A 22.460±2.07 N/A 10.746±7.55
ENST00000356346 N/A 54.747±8.53 12.781±0.00 N/A
ENST00000357649 N/A 11.508±0.01 N/A 2.945±0.00
ENST00000398774 N/A 19.555±4.41 N/A 6.435±1.68
ENST00000436759 N/A 24.228±4.15 N/A 6.430±4.91
ENST00000527096 N/A 23.679±8.61 N/A 9.923±4.73

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0006FZ CIL_0006FZ_0002 CGP
CIL_0007SS CIL_0007SS_0001 VISTA
CIL_0002GS CIL_0002GS_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 NAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008307 IMP structural constituent of muscle
GO:0016528 ISS sarcoplasm
GO:0030056 IDA hemidesmosome
GO:0030198 TAS extracellular matrix organization
GO:0030506 IPI ankyrin binding
GO:0031581 IDA hemidesmosome assembly
GO:0034329 TAS cell junction assembly
GO:0042383 IDA sarcolemma
GO:0043034 TAS costamere
GO:0043292 IEA contractile fiber
GO:0044822 IDA poly(A) RNA binding
GO:0045111 IDA intermediate filament cytoskeleton
GO:0046417 IEA chorismate metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021987 plecb protein_coding Danio_rerio
ENSDARG00000062590 pleca protein_coding Danio_rerio
ENSMUSG00000022565 Plec protein_coding Mus_musculus

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