ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: DAN domain family member 5, BMP antagonist
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179284 DAND5 9606 + 19:12965159-12974762 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317060 DAND5-001 12969482-12974762 protein_coding
  ENST00000585548 DAND5-002 12965159-12974524 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000317060ENST00000585548
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000317060 N/A 0.095±0.08 N/A N/A 0.119±0.08
ENST00000585548 0.092±0.00 0.078±0.05 0.281±0.00 0.174±0.00 0.071±0.05

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007VV CIL_0007VV_0001 VISTA
CIL_0007ZV CIL_0007ZV_0001 VISTA
CIL_0001IU CIL_0001IU_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003140 ISS determination of left/right asymmetry in lateral mesoderm
GO:0003281 ISS ventricular septum development
GO:0003283 ISS atrial septum development
GO:0005515 IEA protein binding
GO:0005576 NAS extracellular region
GO:0007368 IEA determination of left/right symmetry
GO:0016015 ISS morphogen activity
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0030512 ISS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 ISS negative regulation of BMP signaling pathway
GO:0038101 ISS sequestering of nodal from receptor via nodal binding
GO:0061371 ISS determination of heart left/right asymmetry
GO:1900108 ISS negative regulation of nodal signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036471 dand5 protein_coding Danio_rerio
ENSMUSG00000053226 Dand5 protein_coding Mus_musculus

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