ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: early growth response 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179388 EGR3 9606 - 8:22687659-22693302 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317216 EGR3-001 22687659-22693302 protein_coding
  ENST00000518773 EGR3-005 22691165-22692224 processed_transcript
  ENST00000519492 EGR3-002 22690424-22693178 protein_coding
  ENST00000522910 EGR3-003 22690043-22692414 protein_coding
  ENST00000524088 EGR3-004 22690472-22692717 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000317216ENST00000519492ENST00000522910ENST00000524088
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000317216 0.039±0.00 0.049±0.04 0.232±0.00 0.605±2.38
ENST00000519492 N/A 0.231±0.00 N/A N/A
ENST00000522910 N/A N/A 0.248±0.00 0.070±0.05
ENST00000524088 N/A 0.121±0.04 N/A 0.068±0.02

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0002042 IDA cell migration involved in sprouting angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0005634 IBA nucleus
GO:0005737 IBA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007422 IEA peripheral nervous system development
GO:0007517 TAS muscle organ development
GO:0007623 TAS circadian rhythm
GO:0033089 IEA positive regulation of T cell differentiation in thymus
GO:0035767 IMP endothelial cell chemotaxis
GO:0035924 IMP cellular response to vascular endothelial growth factor stimulus
GO:0043066 IMP negative regulation of apoptotic process
GO:0044344 IMP cellular response to fibroblast growth factor stimulus
GO:0045586 IEA regulation of gamma-delta T cell differentiation
GO:0046872 IEA metal ion binding
GO:0071320 IBA cellular response to cAMP
GO:0071371 IBA cellular response to gonadotropin stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089156 egr3 protein_coding Danio_rerio
ENSMUSG00000033730 Egr3 protein_coding Mus_musculus

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