ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: neurexin 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179915 NRXN1 9606 - 2:49918505-51032536 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331040 NRXN1-006 50199137-50656414 processed_transcript
  ENST00000342183 NRXN1-012 49918505-50347754 protein_coding
  ENST00000378262 NRXN1-017 49920349-50019273 protein_coding
  ENST00000401669 NRXN1-003 49921769-51032176 protein_coding
  ENST00000401710 NRXN1-015 49920350-50496076 protein_coding
  ENST00000402717 NRXN1-201 50465443-50623616 protein_coding
  ENST00000404971 NRXN1-002 49920350-51032399 protein_coding
  ENST00000405472 NRXN1-010 49921769-51032112 protein_coding
  ENST00000405581 NRXN1-004 50916822-51032536 protein_coding
  ENST00000406316 NRXN1-001 49920350-51032536 protein_coding
  ENST00000406859 NRXN1-202 50465443-50623616 protein_coding
  ENST00000412315 NRXN1-016 49920349-49974203 protein_coding
  ENST00000462791 NRXN1-009 50497671-50506940 processed_transcript
  ENST00000474354 NRXN1-014 50497575-50528935 retained_intron
  ENST00000484192 NRXN1-011 49920349-49974166 processed_transcript
  ENST00000495871 NRXN1-008 50497679-50620052 processed_transcript
  ENST00000496792 NRXN1-005 50922521-51027781 processed_transcript
  ENST00000611589 NRXN1-203 49921642-50347254 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000342183ENST00000378262ENST00000401710ENST00000402717ENST00000405581ENST00000406316ENST00000412315ENST00000495871ENST00000611589
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000342183 0.009±0.00 0.006±0.00 N/A N/A
ENST00000378262 0.045±0.00 0.031±0.00 N/A 0.016±0.00
ENST00000401710 N/A 0.021±0.00 N/A N/A
ENST00000402717 N/A N/A 0.050±0.00 N/A
ENST00000405581 0.035±0.00 0.007±0.00 N/A 0.004±0.00
ENST00000406316 N/A N/A N/A 0.021±0.00
ENST00000412315 N/A N/A N/A 0.052±0.00
ENST00000495871 N/A N/A N/A 0.024±0.00
ENST00000611589 N/A 0.017±0.01 0.079±0.00 0.014±0.02

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0004872 TAS receptor activity
GO:0005102 ISS receptor binding
GO:0005246 ISS calcium channel regulator activity
GO:0005509 ISS calcium ion binding
GO:0005515 IEA protein binding
GO:0005886 ISS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0007157 ISS heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007158 ISS neuron cell-cell adhesion
GO:0007268 ISS synaptic transmission
GO:0007269 ISS neurotransmitter secretion
GO:0007411 TAS axon guidance
GO:0007416 ISS synapse assembly
GO:0007612 IMP learning
GO:0009986 ISS cell surface
GO:0016021 IEA integral component of membrane
GO:0016339 ISS calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0021707 ISS cerebellar granule cell differentiation
GO:0023041 TAS neuronal signal transduction
GO:0030054 IEA cell junction
GO:0030139 ISS endocytic vesicle
GO:0030198 TAS extracellular matrix organization
GO:0030534 IMP adult behavior
GO:0033130 ISS acetylcholine receptor binding
GO:0035176 IMP social behavior
GO:0035418 ISS protein localization to synapse
GO:0042297 IMP vocal learning
GO:0042734 TAS presynaptic membrane
GO:0044295 ISS axonal growth cone
GO:0045184 ISS establishment of protein localization
GO:0046872 IEA metal ion binding
GO:0048306 ISS calcium-dependent protein binding
GO:0050839 ISS cell adhesion molecule binding
GO:0050885 ISS neuromuscular process controlling balance
GO:0051490 ISS negative regulation of filopodium assembly
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060134 IEA prepulse inhibition
GO:0061178 IEA regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0071625 IMP vocalization behavior
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane
GO:0090129 ISS positive regulation of synapse maturation
GO:0097091 ISS synaptic vesicle clustering
GO:0097104 ISS postsynaptic membrane assembly
GO:0097105 ISS presynaptic membrane assembly
GO:0097109 ISS neuroligin family protein binding
GO:0097112 ISS gamma-aminobutyric acid receptor clustering
GO:0097114 ISS N-methyl-D-aspartate receptor clustering
GO:0097116 ISS gephyrin clustering
GO:0097117 ISS guanylate kinase-associated protein clustering
GO:0097118 ISS neuroligin clustering
GO:0097119 ISS postsynaptic density protein 95 clustering
GO:0097120 ISS receptor localization to synapse
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential
GO:2000821 IEA regulation of grooming behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063150 nrxn2b protein_coding Danio_rerio
ENSMUSG00000024109 Nrxn1 protein_coding Mus_musculus

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